We review the literature for Ran B inding P rotein in the M icrotubule-Organizing Center
(RanBPM; RanBP9), a 90-kDa protein that possesses many characteristics of a scaffolding …

The centrosome, which consists of two centrioles surrounded by pericentriolar material, is a
unique structure that has retained its main features in organisms of various taxonomic …

Mouse oocytes isolated from large antral follicles were exposed to a wide range of
concentrations of bisphenol A (BPA) during maturation in vitro (50ng/ml to 10μg/ml BPA in …

Polo-like kinases (Plks) have several functions in mitotic progression and are upregulated in
many tumor types. Small-molecule Plk inhibitors would be valuable as tools for studying Plk …

YPEL5 is a member of the YPEL gene family that is highly conserved in the eukaryotic
species and apparently involved in a certain cell division-related function. In this study, we …

RanBPM (Ran-binding protein M, also called RanBP9) is an evolutionarily conserved,
ubiquitous protein which localizes to both nucleus and cytoplasm. RanBPM has been …

DNA damage triggers multiple checkpoint pathways to arrest cell cycle progression. Polo-
like kinase 1 (Plk1) is an important regulator of several events during mitosis. In addition to …

Obscurin is an∼ 800-kDa protein composed of structural and signaling domains that
organizes contractile structures in striated muscle. We have studied the Rho-GEF domain of …

Ran-binding protein microtubule-organizing center (RanBPM) appears to function as a
scaffolding protein in several signal transduction pathways. RanBPM is a crucial component …

The centrosome functions as the main microtubule-organization center of the cell and is of
importance for all microtubule-dependent processes such as organelle transport and …