The tooth root is an integral, functionally important part of our dentition. The formation of a
functional root depends on epithelial-mesenchymal interactions and integration of the root …

Reciprocal interactions between epithelial and mesenchymal tissues play a fundamental
role in the morphogenesis of teeth and regulate all aspects of tooth development. Extensive …

Some degree of external root resorption is a frequent, unpredictable, and unavoidable
consequence of orthodontic tooth movement mediated by odontoclasts/cementoclasts …

Canonical Wnt signaling is important in tooth development but it is unclear whether it can
induce cementogenesis and promote the regeneration of periodontal tissues lost because of …

Progenitor cells are crucial in controlling organ morphogenesis. Tooth development is a well‐
established model for investigating the molecular and cellular mechanisms that regulate …

Tooth is made of an enamel-covered crown and a cementum-covered root. Studies on
crown dentin formation have been a major focus in tooth development for several decades …

WNT 10A is a signaling molecule involved in tooth development, and WNT 10A defects are
associated with tooth agenesis. We characterized Wnt10a null mice generated by the …

Coordination between the Hertwig's epithelial root sheath (HERS) and apical papilla (AP) is
crucial for proper tooth root development. The hedgehog (Hh) signaling pathway and Nfic …

The surface structure of bioceramic scaffolds is crucial for its bioactivity and osteoinductive
ability, and in recent years, human periodontal ligament stem cells have been certified to …

Tooth development undergoes a series of complex reciprocal interactions between dental
epithelium and the underlying mesenchymal cells. Compared with the study in tooth crown …