Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Chemically modified platforms for better RNA therapeutics

Y Shi, X Zhen, Y Zhang, Y Li, S Koo, Q Saiding… - Chemical …, 2024 - ACS Publications
RNA-based therapies have catalyzed a revolutionary transformation in the biomedical
landscape, offering unprecedented potential in disease prevention and treatment. However …

Multiple bonds crosslinked antibacterial, conductive and antioxidant hydrogel adhesives with high stretchability and rapid self-healing for MRSA infected motion skin …

W Wang, B Jia, H Xu, Z Li, L Qiao, Y Zhao… - Chemical Engineering …, 2023 - Elsevier
Drug-resistant bacterial infection and low healing efficiency in motion skin wounds impose
significant new requirements on design of wound dressings in terms of flexibility, self …

Supramolecular hydrogels for wound repair and hemostasis

S Zhuo, Y Liang, Z Wu, X Zhao, Y Han, B Guo - Materials Horizons, 2024 - pubs.rsc.org
The unique network characteristics and stimuli responsiveness of supramolecular hydrogels
have rendered them highly advantageous in the field of wound dressings, showcasing …

Recent advances of smart materials for ocular drug delivery

X Wang, F Luan, H Yue, C Song, S Wang… - Advanced drug delivery …, 2023 - Elsevier
Owing to the variety and complexity of ocular diseases and the natural ocular barriers, drug
therapy for ocular diseases has significant limitations, such as poor drug targeting to the site …

Overview of recent advances in nano-based ocular drug delivery

LC Liu, YH Chen, DW Lu - International Journal of Molecular Sciences, 2023 - mdpi.com
Ocular diseases profoundly impact patients' vision and overall quality of life globally.
However, effective ocular drug delivery presents formidable challenges within clinical …

Multifunctional Nanotherapeutics with Long-Acting Release against Macular Degeneration by Minimally Invasive Administration

W Chang, X Lv, J Zhu, JJ Shen, J Yao, Z Liu, Q Chen - ACS nano, 2024 - ACS Publications
Neovascular age-related macular degeneration (AMD), a leading cause of blindness,
requires frequent intravitreal injection of antivascular endothelial growth factor (anti-VEGF) …

Injectable dendrimer hydrogel delivers melphalan in both conjugated and free forms for retinoblastoma

RC Cooper, J Wang, H Yang - Biomacromolecules, 2024 - ACS Publications
We report the successful synthesis of an injectable dendrimer hydrogel (DH) carrying
melphalan, a clinical drug for retinoblastoma treatment, in both conjugated and free forms …

Hydrogels in ophthalmology: Novel strategies for overcoming therapeutic challenges

KY Wu, D Akbar, M Giunta, A Kalevar, SD Tran - Materials, 2023 - mdpi.com
The human eye's intricate anatomical and physiological design necessitates tailored
approaches for managing ocular diseases. Recent advancements in ophthalmology …

Injectable, Antioxidative, and Tissue‐Adhesive Nanocomposite Hydrogel as a Potential Treatment for Inner Retina Injuries

YC Liu, YK Lin, YT Lin, CW Lin, GY Lan… - Advanced …, 2024 - Wiley Online Library
Reactive oxygen species (ROS) have been recognized as prevalent contributors to the
development of inner retinal injuries including optic neuropathies such as glaucoma, non …