Neglected tropical diseases (NTDs) remain major public health problems in developing
countries. Reducing the burden of NTDs requires sustained collaborative drug discovery …

Glycyrrhizae Radix et Rhizoma is the most frequently prescribed natural medicine in China
and has been used for more than 2,000 years. The flavonoids of licorice have garnered …

Licorice, derived from the root of Glycyrrhiza uralensis Fisch, is a key Traditional Chinese
Medicine known for its detoxifying, spleen-nourishing, and qi-replenishing properties …

Licochalcone A (LicoA) is a flavonoid derived from Glycyrrhiza spp. plants. The present
study aimed to investigate the antioxidant, cytotoxic, genotoxic, and chemopreventive effects …

Schistosomiasis, a parasitic disease caused by the blood fluke of the genus Schistosoma,
affects over 230 million people, especially in developing countries. Despite the significant …

Aim: To isolate licochalcone A (LicoA) from licorice, prepare LicoA-loaded solid lipid
nanoparticles (L-SLNs) and evaluate the L-SLNs in vitro and in vivo against Schistosoma …

Schistosomiasis is an infectious tropical disease caused by parasitic flatworm of the genus
Schistosoma. This debilitating disease chronically infects about 200 million people globally …

Background: Neglected tropical diseases (NTDs), including leishmaniasis, trypanosomiasis,
and schistosomiasis, impose a significant public health burden, especially in developing …

Schistosomiasis continues to be a huge challenge for researchers, pharmaceutical
companies, and governments in developing countries. Diterpene compounds are good …

It is estimated that 250 million people worldwide are affected by schistosomiasis. Disease
transmission is related to the poor sanitation and hygiene habits that affect residents of …