Exploring the basic science of prolapse meshes

R Liang, K Knight, S Abramowitch… - Current Opinion in …, 2016 - journals.lww.com
Exploring the basic science of prolapse meshes : Current Opinion in Obstetrics and Gynecology
Exploring the basic science of prolapse meshes : Current Opinion in Obstetrics and Gynecology …

Modeling the flow behavior and flow rate of medium viscosity alginate for scaffold fabrication with a three-dimensional bioplotter

M Sarker, XB Chen - Journal of Manufacturing …, 2017 - asmedigitalcollection.asme.org
Tissue regeneration with scaffolds has proven promising for the repair of damaged tissues
or organs. Dispensing-based printing techniques for scaffold fabrication have drawn …

Biophysical Mechanisms of Vaginal Smooth Muscle Contraction: The Role of the Membrane Potential and Ion Channels

C Mahapatra, R Kumar - Pathophysiology, 2024 - mdpi.com
The vagina is an essential component of the female reproductive system and is responsible
for providing female sexual satisfaction. Vaginal smooth muscle contraction plays a crucial …

Mesh deformation: A mechanism underlying polypropylene prolapse mesh complications in vivo

KM Knight, GE King, SL Palcsey, A Suda, R Liang… - Acta biomaterialia, 2022 - Elsevier
Polypropylene meshes used in pelvic organ prolapse (POP) repair are hampered by
complications. Most POP meshes are highly unstable after tensioning ex vivo, as evidenced …

Extracellular matrix stiffness and composition regulate the myofibroblast differentiation of vaginal fibroblasts

AM Ruiz-Zapata, A Heinz, MH Kerkhof… - International Journal of …, 2020 - mdpi.com
Fibroblast to myofibroblast differentiation is a key feature of wound-healing in soft tissues,
including the vagina. Vaginal fibroblasts maintain the integrity of the vaginal wall tissues …

Electrospun nanofiber meshes with endometrial MSCs modulate foreign body response by increased angiogenesis, matrix synthesis, and anti-inflammatory gene …

S Mukherjee, S Darzi, K Paul, FL Cousins… - Frontiers in …, 2020 - frontiersin.org
Purpose Transvaginal meshes for the treatment of Pelvic Organ Prolapse (POP) have been
associated with severe adverse events and have been banned for clinical use in many …

Composite mesh design for delivery of autologous mesenchymal stem cells influences mesh integration, exposure and biocompatibility in an ovine model of pelvic …

S Emmerson, S Mukherjee, J Melendez-Munoz… - Biomaterials, 2019 - Elsevier
The widespread use of synthetic transvaginal polypropylene mesh for treating Pelvic Organ
Prolapse (POP) has been curtailed due to serious adverse effects highlighted in 2008 and …

Smooth muscle regional contribution to vaginal wall function

GL Clark, AP Pokutta-Paskaleva… - Interface …, 2019 - royalsocietypublishing.org
Pelvic organ prolapse is characterized as the descent of the pelvic organs into the vaginal
canal. In the USA, there is a 12% lifetime risk for requiring surgical intervention. Although …

Smooth muscle contribution to vaginal viscoelastic response

GL Clark-Patterson, LM Buchanan, BO Ogola… - Journal of the …, 2023 - Elsevier
Smooth muscle cells contribute to the mechanical function of various soft tissues, however,
their contribution to the viscoelastic response when subjected to multiaxial loading remains …

Strains induced in the vagina by smooth muscle contractions

A Huntington, SD Abramowitch, PA Moalli, R De Vita - Acta biomaterialia, 2021 - Elsevier
The ability of the vagina to contract gives rise to a set of active mechanical properties that
contribute to the complex function of this organ in-vivo. Regional differences in the …