Droplet-based microfluidics

T Moragues, D Arguijo, T Beneyton, C Modavi… - Nature Reviews …, 2023 - nature.com
Droplet-based microfluidic systems generate, manipulate and control sub-microlitre droplets
enclosed within an immiscible carrier fluid. Owing to a number of remarkable features, such …

Advances in Spheroids and Organoids on a Chip

G Fang, YC Chen, H Lu, D Jin - Advanced Functional Materials, 2023 - Wiley Online Library
Multicellular spheroids and organoids are promising in vitro 3D models in personalized
medicine and drug screening. They replicate the structural and functional characteristics of …

Cell culture in microfluidic droplets

S Sart, G Ronteix, S Jain, G Amselem… - Chemical …, 2022 - ACS Publications
Cell manipulation in droplets has emerged as one of the great successes of microfluidic
technologies, with the development of single-cell screening. However, the droplet format has …

Trends in droplet microfluidics: From droplet generation to biomedical applications

Z Chen, S Kheiri, EWK Young, E Kumacheva - Langmuir, 2022 - ACS Publications
Over the past decade, droplet microfluidics has attracted growing interest in biology,
medicine, and engineering. In this feature article, we review the advances in droplet …

Emerging tumor-on-chips with electrochemical biosensors

L Lei, B Ma, C Xu, H Liu - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Cancer, one of the most dangerous diseases with a high mortality rate, has attracted much
attention and interest. Advances in tissue engineering and microfluidics have led to the …

Recent methods of droplet microfluidics and their applications in spheroids and organoids

Y Wang, M Liu, Y Zhang, H Liu, L Han - Lab on a Chip, 2023 - pubs.rsc.org
Droplet microfluidic techniques have long been known as a high-throughput approach for
cell manipulation. The capacity to compartmentalize cells into picolitre droplets in …

Controllable fusion of human brain organoids using acoustofluidics

Z Ao, H Cai, Z Wu, J Ott, H Wang, K Mackie, F Guo - Lab on a Chip, 2021 - pubs.rsc.org
The fusion of human organoids holds promising potential in modeling physiological and
pathological processes of tissue genesis and organogenesis. However, current fused …

A microfluidic Braille valve platform for on-demand production, combinatorial screening and sorting of chemically distinct droplets

R Utharala, A Grab, V Vafaizadeh, N Peschke… - Nature protocols, 2022 - nature.com
Droplet microfluidics is a powerful tool for a variety of biological applications including single-
cell genetics, antibody discovery and directed evolution. All these applications make use of …

[HTML][HTML] Implementing patient derived organoids in functional precision medicine for patients with advanced colorectal cancer

J Cartry, S Bedja, A Boilève, JRR Mathieu… - Journal of Experimental …, 2023 - Springer
Patient Derived Organoids (PDOs) emerged as the best technology to develop ex vivo tumor
avatars. Whether drug testing on PDOs to identify efficient therapies will bring clinical utility …

Rechargeable self-assembled droplet microswimmers driven by surface phase transitions

D Cholakova, M Lisicki, SK Smoukov, S Tcholakova… - Nature Physics, 2021 - nature.com
The design of artificial microswimmers is often inspired by the strategies of natural
microorganisms. Many of these creatures exploit the fact that elasticity breaks the time …