The transforming growth factor β (TGF-β) family controls many fundamental aspects of
cellular behavior. With advances in the molecular details of the TGF-β signaling cascade …

The transforming growth factor‐beta (TGFβ) superfamily encompasses widespread and
evolutionarily conserved polypeptide growth factors that regulate and orchestrate growth …

The telomere is a special functional complex at the end of linear eukaryotic chromosomes,
consisting of tandem repeat DNA sequences and associated proteins. It is essential for …

TGF-β binding to the cell surface triggers activation of multiple signal transduction pathways
that are connected in intricate ways with each other, and with other response networks …

Transforming growth factor-β1 (TGF-β1) is thought to play a crucial role in fibrotic diseases.
This study demonstrates for the first time that TGF-β1 stimulation can induce myoblasts …

Exercise training is one of the few therapeutic interventions that improves health span by
delaying the onset of age-related diseases and preventing early death. The length of …

Tumorigenesis is in many respects a process of dysregulated cellular evolution that drives
malignant cells to acquire six phenotypic hallmarks of cancer, including their ability to …

Telomerase expression is repressed in most somatic cells but is observed in stem cells and
a high percentage of human cancers and has been hypothesized to contribute to …

Therapeutic progress in adrenocortical carcinoma (ACC) is severely hampered by its low
incidence. Platinum-based chemotherapies are the most effective cytotoxic treatment …

The extremities of eukaryotic chromosomes are called telomeres. They have a structure
unlike the bulk of the chromosome, which allows the cell DNA repair machinery to …