New Findings What is the central question of this study? What are the characteristics of the
NK cell response following acute moderate‐intensity aerobic exercise in prostate cancer …

Perforin secreted from cytotoxic lymphocytes plays a critical role in cancer
immunosurveillance. The aim of this study was to investigate the therapeutic potential of …

Background In the host immune system, perforin is a cytotoxic effector molecule that
eliminate virus-infected and malignant cells. Moreover, some recent studies also imply the …

Advanced prostate cancer (PC) still remains incurable. Novel immunogene therapy shows
promise as treatment strategy that can target both localized and metastasized PC. In this …

Abstract Background and Purpose: Regulatory T cells (Tregs) and NKT cells are two
subpopulations of T lymphocytes that independently regulate innate and adaptive immunity …

GranymeH is a functional cytotoxic serine protease of NK cell granules, which expands the
cell death-inducing repertoire of innate immune system. The purpose of this study was to …

Prostate cancer treatment affects multiple physiological systems, although the immune
response during exercise has been minimally investigated. Purpose: To characterise the …

Perforin (p) is the primary mediator of short term cytotoxicity, it is accumulated in response to
proinflammatory cytokines and stored in T lymphocyte, NK cells and NKT cells are released …

Breast cancer is the most common disease in females and it has become a major health
problem affecting women worldwide. This study was carry out on different groups of female …

GranzymeH is a functional cytotoxic serine protease of NK cell granules, which expands the
cell deathinducing repertoire of innate immune system. The purpose of this study was to …