The life of bacteria is challenging, to endure bacteria employ a range of mechanisms to
optimize their environment, including deploying the type VI secretion system (T6SS). Acting …

Many bacterial species use Type VI secretion systems (T6SSs) to deliver anti-bacterial
effector proteins into neighbouring bacterial cells, representing an important mechanism of …

Type VI secretion systems (T6SSs) are macromolecular assemblies that deliver toxic effector
proteins between adjacent bacteria. These effectors span a wide range of protein families …

Nicotinamide adenine dinucleotide (NAD+) has emerged as a key component in prokaryotic
and eukaryotic immune systems. The recent discovery that Toll/interleukin-1 receptor (TIR) …

Ubiquitination plays essential roles in eukaryotic cellular processes. The effector protein
CteC from Chromobacterium violaceum blocks host ubiquitination by mono-ADP …

The type VI secretion system (T6SS) is a molecular machine utilised by many Gram-negative
bacteria to deliver antibacterial toxins into adjacent cells. Here we present the structure of …

Neisseria meningitidis and Neisseria gonorrhoeae are two obligate human pathogens that
have evolved to be uniquely adapted to their host. The meningococcus is frequently carried …

Aeromonas veronii has a serious impact on the aquaculture industry and human public
health. The type VI secretory system (T6SS) is the virulence regulation system of gram …

Type VI secretion systems (T6SS), recently described in hypervirulent K. pneumoniae (hvKp)
strains, are involved in bacterial warfare but their role in classical clinical strains (cKp) has …

Bacteroidales use type VI secretion systems (T6SS) to competitively colonize and persist in
the colon. We identify a horizontally transferred T6SS with Ntox15 family nuclease effector …