Artificial intelligence in histopathology: enhancing cancer research and clinical oncology

A Shmatko, N Ghaffari Laleh, M Gerstung, JN Kather - Nature cancer, 2022 - nature.com
Artificial intelligence (AI) methods have multiplied our capabilities to extract quantitative
information from digital histopathology images. AI is expected to reduce workload for human …

Artificial intelligence to identify genetic alterations in conventional histopathology

D Cifci, S Foersch, JN Kather - The Journal of Pathology, 2022 - Wiley Online Library
Precision oncology relies on the identification of targetable molecular alterations in tumor
tissues. In many tumor types, a limited set of molecular tests is currently part of standard …

Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study

JM Niehues, P Quirke, NP West, HI Grabsch… - Cell reports …, 2023 - cell.com
Deep learning (DL) can predict microsatellite instability (MSI) from routine histopathology
slides of colorectal cancer (CRC). However, it is unclear whether DL can also predict other …

Self-supervised attention-based deep learning for pan-cancer mutation prediction from histopathology

OL Saldanha, CML Loeffler, JM Niehues… - NPJ Precision …, 2023 - nature.com
The histopathological phenotype of tumors reflects the underlying genetic makeup. Deep
learning can predict genetic alterations from pathology slides, but it is unclear how well …

AI in computational pathology of cancer: improving diagnostic workflows and clinical outcomes?

D Cifci, GP Veldhuizen, S Foersch… - Annual Review of …, 2023 - annualreviews.org
Histopathology plays a fundamental role in the diagnosis and subtyping of solid tumors and
has become a cornerstone of modern precision oncology. Histopathological evaluation is …

Synthetic augmentation with large-scale unconditional pre-training

J Ye, H Ni, P Jin, SX Huang, Y Xue - International Conference on Medical …, 2023 - Springer
Deep learning based medical image recognition systems often require a substantial amount
of training data with expert annotations, which can be expensive and time-consuming to …

Weakly supervised end-to-end artificial intelligence in gastrointestinal endoscopy

L Buendgens, D Cifci, N Ghaffari Laleh… - Scientific Reports, 2022 - nature.com
Artificial intelligence (AI) is widely used to analyze gastrointestinal (GI) endoscopy image
data. AI has led to several clinically approved algorithms for polyp detection, but application …

Predicting the HER2 status in oesophageal cancer from tissue microarrays using convolutional neural networks

JI Pisula, RR Datta, LB Valdez, JR Avemarg… - British Journal of …, 2023 - nature.com
Background Fast and accurate diagnostics are key for personalised medicine. Particularly in
cancer, precise diagnosis is a prerequisite for targeted therapies, which can prolong lives. In …

[HTML][HTML] HistoMIL: A Python package for training multiple instance learning models on histopathology slides

S Pan, M Secrier - Iscience, 2023 - cell.com
Hematoxylin and eosin (H&E) stained slides are widely used in disease diagnosis.
Remarkable advances in deep learning have made it possible to detect complex molecular …