Anticancer property of ginsenoside Rh2 from ginseng

X Li, S Chu, M Lin, Y Gao, Y Liu, S Yang, X Zhou… - European Journal of …, 2020 - Elsevier
Ginseng has been used as a well-known traditional Chinese medicine since ancient times.
Ginsenosides as its main active constituents possess a broad scope of pharmacological …

Ginsenosides: chemistry, biosynthesis, analysis, and potential health effects

LP Christensen - Advances in food and nutrition research, 2008 - Elsevier
Ginsenosides are a special group of triterpenoid saponins that can be classified into two
groups by the skeleton of their aglycones, namely dammarane‐and oleanane‐type …

[HTML][HTML] Terpenoids as potential chemopreventive and therapeutic agents in liver cancer

RJ Thoppil, A Bishayee - World journal of hepatology, 2011 - ncbi.nlm.nih.gov
Despite significant advances in medicine, liver cancer, predominantly hepatocellular
carcinoma remains a major cause of death in the United States as well as the rest of the …

American ginseng: potential structure–function relationship in cancer chemoprevention

LW Qi, CZ Wang, CS Yuan - Biochemical pharmacology, 2010 - Elsevier
Ginseng has a prominent position on the list of best-selling herbal products in the world, and
its main active constituents are thought to be ginsenosides. Compared with the long history …

Biological Activities and Chemistry of Saponins from Panax ginseng CA Meyer

JD Park, DK Rhee, YH Lee - Phytochemistry Reviews, 2005 - Springer
The roots of Panax ginseng CA Meyer, known as Korean ginseng have been a valuable and
important folk medicine in the East Asian countries, such as China, Korea and Japan for …

Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides

PYK Yue, NK Mak, YK Cheng, KW Leung, TB Ng… - Chinese medicine, 2007 - Springer
Abstract In Chinese medicine, ginseng (Panax ginseng CA Meyer) has long been used as a
general tonic or an adaptogen to promote longevity and enhance bodily functions. It has …

The comparative understanding between red ginseng and white ginsengs, processed ginsengs (Panax ginseng CA Meyer)

KY Nam - Journal of Ginseng Research, 2005 - koreascience.kr
Ginseng Radix, the root of Panax ginseng CA Meyer has been used in Eastern Asia for 2000
years as a tonic and restorative, promoting health and longevity. Two varieties are …

Structure–function relationship exists for ginsenosides in reducing cell proliferation and inducing apoptosis in the human leukemia (THP-1) cell line

DG Popovich, DD Kitts - Archives of Biochemistry and Biophysics, 2002 - Elsevier
Ginsenosides of the 20 (S)-protopanaxadiol and 20 (S)-protopanaxatriol classifications
including the aglycones, protopanaxadiol (PD), protopanaxatriol (PT), and ginsenosides …

Anti-proliferating effects of ginsenoside Rh2 on MCF-7 human breast cancer cells.

M Oh, YH Choi, S Choi, H Chung… - International …, 1999 - spandidos-publications.com
Abstract Ginsenoside Rh2 (G-Rh2) isolated from the root of Panax ginseng has been shown
to have anti-cancer proliferation, differentiation and chemopreventive effects in certain …

Activation of caspase-3 protease via a Bcl-2-insensitive pathway during the process of ginsenoside Rh2-induced apoptosis

JA Park, KY Lee, YJ Oh, KW Kim, SK Lee - Cancer letters, 1997 - Elsevier
We have demonstrated that ginsenoside Rh2 (G-Rh2), a ginseng saponin with a
dammarane skeleton, induces apoptosis of human hepatoma SK-HEP-1 cells as evidenced …