Quiescence is a state of reversible proliferative arrest in which cells are not actively dividing
and yet retain the capacity to reenter the cell cycle upon receiving an appropriate stimulus …

Satellite cells are required for the growth, maintenance, and regeneration of skeletal muscle.
Quiescent satellite cells possess a primary cilium, a structure that regulates the processing …

Cell proliferation control is essential during development and for maintaining adult tissues.
Loss of that control promotes not only oncogenesis when cells proliferate inappropriately but …

Acetylation is the most studied histone acyl modification and has been recognized as a
fundamental player in metabolic gene regulation, whereas other short-chain acyl …

Central nervous system (CNS) lesions become surrounded by neuroprotective borders of
newly proliferated reactive astrocytes; however, fundamental features of these cells are …

Signaling interactions are important during skeletal muscle regeneration, where muscle
cells in distinct states (quiescent, reactivated, proliferating and differentiated) must …

Cisplatin, a platinum-based anticancer drug, is used to treat several types of cancer. Despite
its effectiveness, cisplatin-induced side effects have often been reported. Although cisplatin …

Vascular endothelial cells are exposed to mechanical forces due to their presence at the
interface between the vessel wall and flowing blood. The patterns of these mechanical …

Skeletal muscle stem cells (MuSC) are crucial for tissue homoeostasis and repair after
injury. Following activation, they proliferate to generate differentiating myoblasts. A …

Primary cilia are non-motile, cell cycle-associated organelles that can be found on most
vertebrate cell types. Comprised of microtubule bundles organised into an axoneme and …