Rationale: Acute lung dysfunction of noninfectious etiology, known as idiopathic pneumonia
syndrome (IPS), is a severe complication following hematopoietic stem cell transplantation …

Large numbers of patients now survive long term following stem cell transplantation (SCT).
The late clinical effects of SCT are thus of major concern in the 21st century. Secondary …

A variant of the autophagy gene ATG16L1 is associated with Crohn's disease, an
inflammatory bowel disease (IBD), and poor survival in allogeneic hematopoietic stem cell …

Mesenchymal stem cells (MSCs) have fueled ample translation for the treatment of immune‐
mediated diseases. They exert immunoregulatory and tissue‐restoring effects. MSC …

Alloantigen expression on host antigen-presenting cells (APCs) is essential to initiate graft-
versus-host disease (GvHD); therefore, alloantigen expression on host target epithelium is …

The ability to successfully transplant solid organs and hematopoietic stem cells represents
one of the landmark medical achievements of the twentieth century. Solid organ …

Bone marrow-derived cells are known to play important roles in repair/regeneration of
injured tissues, but their roles in pathological fibrosis are less clear. Here, we report a critical …

Alloantigen expression on host APCs is essential to initiate graft-vs-host disease (GVHD);
however, critical APC subset remains to be elucidated. We compared the ability of dendritic …

Chronic graft-versus-host disease (GVHD) is a major cause of morbidity and mortality in long-
term survivors of allogeneic stem cell transplantation. The immunopathogenesis of chronic …

Allogeneic hematopoietic cell transplantation (HCT) is effective therapy for hematologic
malignancies through T cell–mediated GVL effects. However, HCT benefits are frequently …