Transfer and functional consequences of dietary microRNAs in vertebrates: concepts in search of corroboration: negative results challenge the hypothesis that dietary …

KW Witwer, KD Hirschi - Bioessays, 2014 - Wiley Online Library
If validated, diet‐derived foreign microRNA absorption and function in consuming
vertebrates would drastically alter our understanding of nutrition and ecology. RNA …

Proteogenomics: integrating next-generation sequencing and mass spectrometry to characterize human proteomic variation

GM Sheynkman, MR Shortreed… - Annual review of …, 2016 - annualreviews.org
Mass spectrometry–based proteomics has emerged as the leading method for detection,
quantification, and characterization of proteins. Nearly all proteomic workflows rely on …

Challenges in defining the role of intron retention in normal biology and disease

DP Vanichkina, U Schmitz, JJL Wong… - Seminars in cell & …, 2018 - Elsevier
RNA sequencing has revealed a striking diversity in transcriptomic complexity, to which
alternative splicing is a major contributor. Intron retention (IR) is a conserved form of …

Proteomic validation of transcript isoforms, including those assembled from RNA-Seq data

AP Tay, CNI Pang, NA Twine… - Journal of Proteome …, 2015 - ACS Publications
Human proteome analysis now requires an understanding of protein isoforms. We recently
published the PG Nexus pipeline, which facilitates high confidence validation of exons and …

A tool for integrating genetic and mass spectrometry‐based peptide data: Proteogenomics Viewer: PV: A genome browser‐like tool, which includes MS data …

JE Kroll, VL da Silva, SJ de Souza, GA de Souza - Bioessays, 2017 - Wiley Online Library
In this manuscript we describe Proteogenomics Viewer, a web‐based tool that collects MS
peptide identification, indexes to genomic sequence and structure, assigns exon usage …

A predicted novel protein isoform of HOXA9

JWD Wang, GL Gross, ER Andrew, A Padovan… - Leukemia Research, 2019 - Elsevier
2. Methods The alternate protein isoform in mouse was previously predicted [16]. For
verification of other species, sequence data were downloaded from ENSEMBL and NCBI …