Almost every cell has a molecular clock, which controls gene expression on a 24-h cycle,
providing circadian rhythmicity. An example of a circadian behaviour common to most …

Tumors develop by invoking a supportive environment characterized by aberrant
angiogenesis and infiltration of tumor-associated macrophages (TAMs). In a transgenic …

Neutrophil extracellular traps (NETs) participate in the rapid inhibition and clearance of
pathogens during infection; however, the molecular regulation of NET formation remains …

The interaction between the nervous and immune systems during aging is an area of avid
interest, but many aspects remain unclear. This is due, not only to the complexity of the …

Spaceflight-associated immune system weakening ultimately limits the ability of humans to
expand their presence beyond the earth's orbit. A mechanistic study of microgravity …

Macrophages acquire distinct phenotypes during tissue stress and inflammatory responses.
Macrophages are roughly categorized into two different subsets named inflammatory M1 …

Fatty acid binding protein 5 (FABP5) is mainly involved in the uptake, transport, and
metabolism of fatty acid in the cytoplasm, and its role in immune cells has been recognized …

Background Excessive inflammation and cell death induced by ultraviolet (UV) cause skin
photodamage. Metformin possesses anti-inflammatory and cytoprotective effects. However …

Bilirubin, as the final product of heme metabolism, has both toxic and beneficial effects on
humans depending on its serum concentration. So far, whether and how physiological …

Persistent infection with high-risk human papillomavirus (HPV) is a prerequisite for the
development of cervical cancer. HPV-transformed cells actively instruct their …