The mean of milk: a review of human milk oligosaccharide concentrations throughout lactation

B Soyyılmaz, MH Mikš, CH Röhrig, M Matwiejuk… - Nutrients, 2021 - mdpi.com
Human milk oligosaccharides (HMOs) are non-digestible and structurally diverse complex
carbohydrates that are highly abundant in human milk. To date, more than 200 different …

Mass spectrometry approaches to glycomic and glycoproteomic analyses

LR Ruhaak, G Xu, Q Li, E Goonatilleke… - Chemical …, 2018 - ACS Publications
Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides
(glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate …

Systematic review of the concentrations of oligosaccharides in human milk

S Thurl, M Munzert, G Boehm, C Matthews… - Nutrition …, 2017 - academic.oup.com
Context Oligosaccharides are the third largest solid component in human milk. These
diverse compounds are thought to have numerous beneficial functions in infants, including …

Effects of infant formula with human milk oligosaccharides on growth and morbidity: a randomized multicenter trial

G Puccio, P Alliet, C Cajozzo, E Janssens… - Journal of pediatric …, 2017 - journals.lww.com
Objectives: The aim of the study was to evaluate the effects of infant formula supplemented
with 2 human milk oligosaccharides (HMOs) on infant growth, tolerance, and morbidity …

Creation of a milk oligosaccharide database, MilkOligoDB, reveals common structural motifs and extensive diversity across mammals

SD Durham, Z Wei, DG Lemay, MC Lange, D Barile - Scientific reports, 2023 - nature.com
The carbohydrate fraction of most mammalian milks contains a variety of oligosaccharides
that encompass a range of structures and monosaccharide compositions. Human milk …

The association between breastmilk oligosaccharides and faecal microbiota in healthy breastfed infants at two, six, and twelve weeks of age

K Borewicz, F Gu, E Saccenti, C Hechler, R Beijers… - Scientific reports, 2020 - nature.com
Several factors affect gut microbiota development in early life, among which breastfeeding
plays a key role. We followed 24 mother-infant pairs to investigate the associations between …

Changes in HMO concentrations throughout lactation: influencing factors, health effects and opportunities

C Thum, CR Wall, GA Weiss, W Wang, IMY Szeto… - Nutrients, 2021 - mdpi.com
Human milk oligosaccharides (HMOs) are important functional biomolecules in human
breast milk. Understanding the factors influencing differences in HMO composition and …

[HTML][HTML] Absolute quantitation of human milk oligosaccharides reveals phenotypic variations during lactation

G Xu, JCC Davis, E Goonatilleke, JT Smilowitz… - The Journal of …, 2017 - Elsevier
Background The quantitation of human milk oligosaccharides (HMOs) is challenging
because of the structural complexity and lack of standards. Objective The objective of our …

Characterization of isomeric glycan structures by LC‐MS/MS

L Veillon, Y Huang, W Peng, X Dong, BG Cho… - …, 2017 - Wiley Online Library
The characterization of glycosylation is critical for obtaining a comprehensive view of the
regulation and functions of glycoproteins of interest. Due to the complex nature of …

Enzymatic and cell factory approaches to the production of human milk oligosaccharides

M Faijes, M Castejón-Vilatersana, C Val-Cid… - Biotechnology …, 2019 - Elsevier
Infant formula milk companies try to develop fortified formula milk that mimics human milk as
closely as possible, since it is well-known that breast milk has considerable implications in …