Enantioenriched fluorinated α‐and β‐amino acids are often encountered in numerous
pharmaceuticals and bioactive molecules, and also of great importance as probes in PET …

The aim of this review is to highlight the rich chemistry of α‐haloamides originally mainly
used to discover new C− N, C− O and C− S bond forming reactions, and later widely …

A Mn‐catalyzed diastereo‐and enantioselective hydrogenation of α‐substituted β‐
ketoamides has been realized for the first time under dynamic kinetic resolution conditions …

β-Amino acid derivatives are key structural elements in synthetic and biological chemistry.
Despite being a hallmark method for their preparation, the direct Mannich reaction …

Catalytic asymmetric Mannich reactions of imines with weakly acidic simple amides were
developed using a chiral potassium hexamethyldisilazide (KHMDS)–bis (oxazoline) …

The stereoselective preparation of 1, 2, 3-substituted cyclopropanes from α, β-unsaturated
carbonyl compounds in the carboxylic acid oxidation state through Michael addition-initiated …

A direct and asymmetric syn-aldol reaction of N-acyl-1, 3-oxazinane-2-thiones with dialkyl
acetals from aromatic acetals in the presence of 2–5 mol%[DTBM-SEGPHOS] NiCl2 …

Carboxylic acids, amides, and esters are ubiquitous motifs in functional organic molecules.
However, the reactivities of these high oxidation state carbonyl compounds are far lower …

Abstract α‐Oxygen‐functionalized amides found particular utility as enolate surrogates for
direct aldol couplings with α‐fluorinated ketones in a catalytic manner. Because of the likely …

Here we report the highly enantio-and syn-selective synthesis of β-hydroxy α-amino acids
from glycine imine derivatives under Brønsted base (BB) catalysis. The key of this approach …