The vagina has been considered a potential drug administration route for centuries. Most of
the currently marketed and investigated vaginal formulations are composed with the use of …

Polymeric nanomaterials have become a prominent area of research in the field of drug
delivery. Their application in nanomedicine can improve bioavailability, pharmacokinetics …

The stratum corneum, the most superficial layer of the skin, protects the body against
environmental hazards and presents a highly selective barrier for the passage of drugs and …

Currently, the significance of fungi as human pathogens is not medically concealed in the
world. Consequently, suitable recognition and treatment of such infections are of great …

Fungal infections have become a major health concern, given that invasive infections by
Candida, Cryptococcus, and Aspergillus species have led to millions of mortalities …

There are four major classes of antifungals with the predominant mechanism of action being
targeting of cell wall or cell membrane. As in other drugs, low solubility of these compounds …

The crescent number of cases of candidiasis and the increase in the number of infections
developed by non-albicans species and by multi-resistant strains has taken the attention of …

Fenticonazole nitrate (FTN) is a potent antifungal drug adopted in the treatment of vaginal
candidiasis. It has inadequate aqueous solubility hence, novel ultra-deformable liposomes …

There is a growing clinical demand for topical itraconazole (ITC) delivery systems because
of the expanding potential of the drug for topical fungal and non-fungal applications. Lipid …

Vaginal infections such as bacterial vaginosis (BV), chlamydia, gonorrhea, genital herpes,
candidiasis, and trichomoniasis affect millions of women each year. They are caused by an …