Langerhans cell histiocytosis in children–a disease with many faces. Recent advances in pathogenesis, diagnostic examinations and treatment

M Jezierska, J Stefanowicz, G Romanowicz… - … in Dermatology and …, 2018 - termedia.pl
Langerhans cell histiocytosis is a rare clonal disease characterized by the proliferation of
CD1a-positive immature dendritic cells. The purpose of this article was to present an …

Recent advances in Langerhans cell histiocytosis

A Morimoto, Y Oh, Y Shioda, K Kudo… - Pediatrics …, 2014 - Wiley Online Library
The purpose of this review is to provide an updated overview of the pathogenesis and
treatment of Langerhans cell histiocytosis (LCH). The pathogenesis of LCH remains obscure …

[HTML][HTML] Additive prognostic impact of gastrointestinal involvement in severe multisystem Langerhans cell histiocytosis

M Minkov, U Pötschger, N Thacker, I Astigarraga… - The journal of …, 2021 - Elsevier
Objective To evaluate the prognostic impact of gastrointestinal involvement (GI-LCH) on the
survival of children with Langerhans cell histiocytosis registered on the international clinical …

Imaging of histiocytosis in the era of genomic medicine

H Park, M Nishino, JL Hornick, ED Jacobsen - Radiographics, 2019 - pubs.rsna.org
Histiocytosis describes a group of diseases that have long been considered enigmatic in the
history of medicine. Recently, novel genomic analyses have identified somatic oncogenic …

Clinicopathologic Features of Gastrointestinal Tract Langerhans Cell Histiocytosis

S Hu, RP Graham, WT Choi, KW Wen, J Putra, W Chen… - Modern Pathology, 2024 - Elsevier
Gastrointestinal (GI) tract involvement by Langerhans cell histiocytosis (LCH) is rare and its
clinicopathologic characteristics have only been described in case reports and small series …

Langerhans cell histiocytosis misdiagnosed as cow protein allergy: a case report

X Lv, L Wang, Z Pi, C Zhang - BMC pediatrics, 2021 - Springer
Background Langerhans cell histiocytosis (LCH) is a heterogeneous disease with diverse
clinical manifestations. Abdominal organ involvement is rare. Early diagnosis and active …

Langerhans cell histiocytosis involving the gastrointestinal tract

A Behdad, SR Owens - Archives of Pathology and …, 2014 - meridian.allenpress.com
Langerhans cell histiocytosis is a rare disease with a variable clinical presentation, and its
prognosis and treatment depend on the extent and severity of disease. Although the …

Manifestations and outcomes of digestive tract involvement in adult Langerhans cell histiocytosis

Q Shang, L Chang, M Lang, Z Liu, H Lin, J Zhao… - Annals of …, 2024 - Springer
Langerhans cell histiocytosis (LCH) is a heterogeneous histiocytosis characterized by
proliferation of Langerhans cells. While less common, manifestations of digestive tract …

[PDF][PDF] Intestinal Langerhans cell histiocytosis presenting with symptoms similar to inflammatory bowel disease: a case report

Y Liu, Z Chen, L Wang, B Li - Pathology and Oncology Research, 2024 - por-journal.com
Background: Langerhans cell histiocytosis is a rare disease characterized by the abnormal
proliferation of Langerhans cells within a single organ or multiple organs. This case report …

Adult‐onset systemic L angerhans cell histiocytosis mimicking inflammatory bowel disease: the value of skin biopsy and review of cases of L angerhans cell …

JO Podjasek, CG Loftus, TC Smyrk… - International journal of …, 2014 - Wiley Online Library
Background Langerhans cell histiocytosis (LCH) is frequently known to involve multiple
organ systems. However, gastrointestinal involvement by LCH is rare. Methods We describe …