It has been 15 years since the birth of human induced pluripotent stem cell (iPSC)
technology in 2007, and the scope of its application has been expanding. In addition to the …

Alzheimer's disease (AD), Parkinson's disease (PD), and Amyotrophic Lateral Sclerosis
(ALS) are representative neurodegenerative diseases (NDs) characterized by degeneration …

The engineering of osteochondral interfaces remains a challenge. MicroRNAs (miRs) have
emerged as significant tools to regulate the differentiation and proliferation of osteogenic …

The challenges in making animal models of complex human epilepsy phenotypes with
varied aetiology highlights the need to develop alternative disease models that can address …

Destruction and death of neurons can lead to neurodegenerative diseases. One possible
way to treat neurodegenerative diseases and damage of the nervous system is replacing …

Background Microglia are innate immune cells that are the only residential macrophages in
the central nervous system. They play vital physiological roles in the adult brain and during …

Alzheimer's disease (AD) is a neurodegenerative disease with dysfunction of memory,
language and thinking. More than 55 million people were diagnosed with AD or other …

Early in vivo embryonic retinal development is a well-documented and evolutionary
conserved process. The specification towards eye development is temporally controlled by …

Neuronal miRNA dysregulation may have a role in the pathophysiology of Alzheimer's
disease (AD). miRNA (miR)-124 is largely abundant and a critical player in many neuronal …

Stem cell science is among the fastest moving fields in biology, with many highly promising
directions for translatability. To centralize and contextualize some of the latest …