Neural activity is intimately tied to blood flow in the brain. This coupling is specific enough in
space and time that modern imaging methods use local hemodynamics as a measure of …

Epilepsy comprises a group of disorders characterized by the periodic occurrence of
seizures, and pathologic specimens from patients with temporal lobe epilepsy demonstrate …

Epilepsy, affecting about 1% of the population, comprises a group of disorders of the brain
characterized by the periodic and unpredictable occurrence of seizures. Epilepsy is a major …

1. Abstract Background Current concepts of Attention-Deficit/Hyperactivity Disorder (ADHD)
emphasize the role of higher-order cognitive functions and reinforcement processes …

Astrocytes play an essential role in the development of neural circuits by positioning
transporters and receptors near synapses and secreting factors that promote synaptic …

Metabotropic glutamate (mGlu) receptors respond to glutamate, the major excitatory
neurotransmitter in the mammalian brain, mediating a modulatory role that is critical for …

Diabetes impacts on brain metabolism, structure, and function. Alterations in brain
metabolism have been observed in obesity and diabetes models induced by exposure to …

Glutamate is a major excitatory neurotransmitter in the CNS that is involved in numerous
cellular functions, including cell death and survival. Metabotropic glutamate receptors …

We investigated whether the activation of astroglial group II and III metabotropic glutamate
receptors (mGluRs) could exert neuroprotective effects and whether the neuroprotection was …

Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system
(CNS) and exerts its actions via a number of ionotropic glutamate receptors/channels and …