The cellular and molecular basis for planarian regeneration

PW Reddien - Cell, 2018 - cell.com
Regeneration is one of the great mysteries of biology. Planarians are flatworms capable of
dramatic feats of regeneration, which have been studied for over 2 centuries. Recent …

Model systems for regeneration: planarians

M Ivankovic, R Haneckova, A Thommen… - …, 2019 - journals.biologists.com
Planarians are a group of flatworms. Some planarian species have remarkable regenerative
abilities, which involve abundant pluripotent adult stem cells. This makes these worms a …

Wnt/β-catenin signalling is required for pole-specific chromatin remodeling during planarian regeneration

E Pascual-Carreras, M Marín-Barba… - Nature …, 2023 - nature.com
For successful regeneration, the identity of the missing tissue must be specified according to
the pre-existing tissue. Planarians are ideal for the study of the mechanisms underlying this …

[HTML][HTML] Wnt/β-catenin signaling in heart regeneration

G Ozhan, G Weidinger - Cell regeneration, 2015 - Elsevier
The ability to repair damaged or lost tissues varies significantly among vertebrates. The
regenerative ability of the heart is clinically very relevant, because adult teleost fish and …

PlanMine–a mineable resource of planarian biology and biodiversity

H Brandl, HK Moon, M Vila-Farré, SY Liu… - Nucleic acids …, 2016 - academic.oup.com
Planarian flatworms are in the midst of a renaissance as a model system for regeneration
and stem cells. Besides two well-studied model species, hundreds of species exist …

An evolutionarily-conserved Wnt3/β-catenin/Sp5 feedback loop restricts head organizer activity in Hydra

MC Vogg, L Beccari, L Iglesias Ollé, C Rampon… - Nature …, 2019 - nature.com
Polyps of the cnidarian Hydra maintain their adult anatomy through two developmental
organizers, the head organizer located apically and the foot organizer basally. The head …

Antagonistic self-organizing patterning systems control maintenance and regeneration of the anteroposterior axis in planarians

T Stückemann, JP Cleland, S Werner, HTK Vu… - Developmental cell, 2017 - cell.com
Planarian flatworms maintain their body plan in the face of constant internal turnover and
can regenerate from arbitrary tissue fragments. Both phenomena require self-maintaining …

Two FGFRL-Wnt circuits organize the planarian anteroposterior axis

ML Scimone, LE Cote, T Rogers, PW Reddien - Elife, 2016 - elifesciences.org
How positional information instructs adult tissue maintenance is poorly understood.
Planarians undergo whole-body regeneration and tissue turnover, providing a model for …

An insight into planarian regeneration

XY Ge, X Han, YL Zhao, GS Cui, YG Yang - Cell Proliferation, 2022 - Wiley Online Library
Background Planarian has attracted increasing attentions in the regeneration field for its
usefulness as an important biological model organism attributing to its strong regeneration …

Positional information and stem cells combine to result in planarian regeneration

PW Reddien - Cold Spring Harbor Perspectives in …, 2022 - cshperspectives.cshlp.org
The capacity for regeneration is broad in the animal kingdom. Planarians are flatworms that
can regenerate any missing body part and their regenerative powers have combined with …