The immunology of Plasmodium vivax malaria

LR Antonelli, C Junqueira, JM Vinetz… - Immunological …, 2020 - Wiley Online Library
Plasmodium vivax infection, the predominant cause of malaria in Asia and Latin America,
affects~ 14 million individuals annually, with considerable adverse effects on wellbeing and …

Natural acquisition of immunity to Plasmodium vivax: epidemiological observations and potential targets

I Mueller, MR Galinski, T Tsuboi… - Advances in …, 2013 - Elsevier
Population studies show that individuals acquire immunity to Plasmodium vivax more
quickly than Plasmodium falciparum irrespective of overall transmission intensity, resulting …

Duffy Negative Antigen Is No Longer a Barrier to Plasmodium vivax – Molecular Evidences from the African West Coast (Angola and Equatorial Guinea)

C Mendes, F Dias, J Figueiredo, VG Mora… - PLoS neglected …, 2011 - journals.plos.org
Background Plasmodium vivax shows a small prevalence in West and Central Africa due to
the high prevalence of Duffy negative people. However, Duffy negative individuals infected …

Potential contribution of sero‐epidemiological analysis for monitoring malaria control and elimination: historical and current perspectives

C Drakeley, J Cook - Advances in parasitology, 2009 - Elsevier
Anti‐malarial antibody responses represent an individual's history of exposure to the
disease and, as age sero‐conversion rates, reflect cumulative malaria exposure in a …

Insights into the naturally acquired immune response to Plasmodium vivax malaria

RJ Longley, J Sattabongkot, IVO Mueller - Parasitology, 2016 - cambridge.org
Plasmodium vivax is the most geographically widespread of the malaria parasites causing
human disease, yet it is comparatively understudied compared with Plasmodium falciparum …

Novel insights into Plasmodium vivax therapeutic failure: CYP2D6 activity and time of exposure to malaria modulate the risk of recurrence

ACR Silvino, FS Kano, MA Costa… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
Plasmodium vivax relapse is one of the major causes of sustained global malaria
transmission. Primaquine (PQ) is the only commercial drug available to prevent relapses …

Susceptibility to Plasmodium vivax malaria associated with DARC (Duffy antigen) polymorphisms is influenced by the time of exposure to malaria

FS Kano, AM de Souza, L de Menezes Torres… - Scientific reports, 2018 - nature.com
Malaria has provided a major selective pressure and has modulated the genetic diversity of
the human genome. The variants of the Duffy Antigen/Receptor for Chemokines (DARC) …

Naturally acquired inhibitory antibodies to Plasmodium vivax Duffy binding protein are short-lived and allele-specific following a single malaria infection

IP Ceravolo, BAM Sanchez, TN Sousa… - Clinical & …, 2009 - academic.oup.com
The Duffy binding protein of Plasmodium vivax (DBP) is a critical adhesion ligand that
participates in merozoite invasion of human Duffy-positive erythrocytes. A small outbreak of …

Structural Analysis of the Synthetic Duffy Binding Protein (DBP) Antigen DEKnull Relevant for Plasmodium vivax Malaria Vaccine Design

E Chen, ND Salinas, FB Ntumngia… - PLoS neglected …, 2015 - journals.plos.org
The Plasmodium vivax vaccine candidate Duffy Binding Protein (DBP) is a protein
necessary for P. vivax invasion of reticulocytes. The polymorphic nature of DBP induces …

[HTML][HTML] A survey of malaria and some arboviral infections among suspected febrile patients visiting a health centre in Simawa, Ogun State, Nigeria

AF Ayorinde, AM Oyeyiga, NO Nosegbe… - Journal of Infection and …, 2016 - Elsevier
Most febrile patients are often misdiagnosed with malaria due to similar symptoms, such as
fever shared by malaria and certain arboviral infections. This study surveyed the incidence …