Chronic hepatitis B virus (HBV) infection is a common cause of liver disease globally, with a
disproportionately high burden in South-East Asia. Vaccines and nucleoside or nucleotide …

Charge detection mass spectrometry (CDMS) is a single-particle technique where the
masses of individual ions are determined from simultaneous measurement of their mass-to …

Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell
called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review …

Abstract Hepatitis B Virus (HBV) is a small virus whose genome has only four open reading
frames. We argue that the simplicity of the virion correlates with a complexity of functions for …

The core (capsid) protein of hepatitis B virus (HBV) is the building block of nucleocapsids
where viral DNA reverse transcriptional replication takes place and mediates virus-host cell …

Hepatitis B virus is one of the smallest human pathogens, encoded by a 3,200-bp genome
with only four open reading frames. Yet the virus shows a remarkable diversity in structural …

Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and
is mediated by the core protein. Due to its multiple functions in the viral life cycle, core …

Hepatitis B virus (HBV) infection affects approximately 300 million people worldwide.
Although antiviral therapies have improved the long-term outcomes, patients often require …

The assembly of hepatitis B virus (HBV) core protein (HBc) into capsids represents a critical
step of viral replication. HBc has multiple functions during the HBV life cycle, which makes it …

Chronic hepatitis B virus (HBV) infection, a serious public health problem leading to cirrhosis
and hepatocellular carcinoma, is currently treated with either pegylated alpha interferon …