Emerging viruses such as HIV, dengue, influenza A, SARS coronavirus, Ebola, and other
viruses pose a significant threat to human health. Majority of these viruses are responsible …

Autophagy (self-eating) is a conserved cellular degradation process that plays important
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …

Lacking a self-contained metabolism network, viruses have evolved multiple mechanisms
for rewiring the metabolic system of their host to hijack the host's metabolic resources for …

Influenza A virus (IAV) infection induces mitophagy, which is essential for the clearance of
damaged mitochondria. Dysfunctional mitochondria can be selectively targeted by PINK1 …

Autophagy is a constitutive cellular process of degradation required to maintain homeostasis
and turn over spent organelles and aggregated proteins. For some viruses, the process can …

Paramyxovirus establishes an intimate and complex interaction with the host cell to
counteract the antiviral responses elicited by the cell. Of the various pattern recognition …

Influenza A virus can evade host innate immune response that is involved in several viral
proteins with complicated mechanisms. To date, how influenza A M2 protein modulates the …

Newcastle disease virus (NDV), a member of the Paramyxoviridae family, can activate
PKR/eIF2α signaling cascade to shutoff host and facilitate viral mRNA translation during …

In addition to direct oncolysis, oncolytic viruses trigger immunogenic cell death (ICD) and
primes antitumor immunity. We have previously shown that oncolytic Newcastle disease …

Autophagy is an evolutionarily conserved process central to host metabolism. Among its
major functions are conservation of energy during starvation, recycling organelles, and …