[HTML][HTML] Structure-function and engineering of plant UDP-glycosyltransferase

M Wang, Q Ji, B Lai, Y Liu, K Mei - Computational and Structural …, 2023 - Elsevier
Natural products synthesized by plants have substantial industrial and medicinal values and
are therefore attracting increasing interest in various related industries. Among the key …

[HTML][HTML] The favorable impacts of silibinin polyphenols as adjunctive therapy in reducing the complications of COVID-19: A review of research evidence and …

V Musazadeh, A Karimi, J Jafarzadeh, S Sanaie… - Biomedicine & …, 2022 - Elsevier
The proceeding pandemic of coronavirus disease 2019 is the latest global challenge. Like
most other infectious diseases, inflammation, oxidative stress, and immune system …

Chemoenzymatic indican for light-driven denim dyeing

GN Bidart, D Teze, CU Jansen, E Pasutto… - Nature …, 2024 - nature.com
Blue denim, a billion-dollar industry, is currently dyed with indigo in an unsustainable
process requiring harsh reducing and alkaline chemicals. Forming indigo directly in the yarn …

Identification and Functional Characterization of UDP-Glycosyltransferases Involved in Isoflavone Biosynthesis in Astragalus membranaceus

Y Hao, J Fu, J Zhang, N Du, H Ta, TT Zhu… - Journal of Agricultural …, 2023 - ACS Publications
Isoflavones are rich natural compounds present in legumes and are essential for plant
growth and development. Moreover, they are beneficial for animals and humans …

Structurefunction relationships in plant UDP-glycosyltransferases

J Yao, X Xing, L Yu, Y Wang, X Zhang… - Industrial Crops and …, 2022 - Elsevier
Uridine diphosphate-dependent glycosyltransferases (UGTs) in plants catalyze O-, C-, S-
and N-glycosylation of diverse substrates to yield a wide variety of glycosides with broad …

A comparative molecular dynamics approach guides the tailoring of glycosyltransferases to meet synthetic applications

P Zhang, S Meng, Z Li, D Hirtz, L Elling, L Zhu, Y Ji… - Green …, 2024 - pubs.rsc.org
The properties of natural products can be significantly influenced by glycosylation,
emphasizing the key role of glycosyltransferases (GTs) in this process. The pursuit of …

Promiscuous Yet Specific: A Methionine–Aromatic Interaction Drives the Reaction Scope of the Family 1 Glycosyltransferase GmUGT88E3 from Soybean

RM de Boer, DE H. Hvid, E Davail, D Vaitkus… - Biochemistry, 2023 - ACS Publications
Family 1 glycosyltransferases (GT1s, UGTs) catalyze the regioselective glycosylation of
natural products in a single step. We identified Gm UGT88E3 as a particularly promising …

Family 1 glycosyltransferases (GT1, UGTs) are subject to dilution-induced inactivation and low chemo stability toward their own acceptor substrates

D Teze, GN Bidart, DH Welner - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Glycosylation reactions are essential but challenging from a conventional chemistry
standpoint. Conversely, they are biotechnologically feasible as glycosyltransferases can …

Exploring the efficacy of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a natural compound in strengthening maize resistance against biotic and abiotic stressors …

S Debnath, AM Elgorban, AH Bahkali… - Frontiers in …, 2023 - frontiersin.org
Objective This study aims to understand plant-bacteria interactions that enhance plant
resistance to environmental stressors, with a focus on maize (Zea mays L.) and its …

Insights into functional divergence, catalytic versatility and specificity of small molecule glycosyltransferases

P Srivastava, S Ghosh - International Journal of Biological Macromolecules, 2024 - Elsevier
Glycosylation is one of the most fundamental biochemical processes in cells. It plays crucial
roles in diversifying plant natural products for structures, bioavailability and bioactivity, and …