The biomedical use of silk: past, present, future

C Holland, K Numata… - Advanced healthcare …, 2019 - Wiley Online Library
Humans have long appreciated silk for its lustrous appeal and remarkable physical
properties, yet as the mysteries of silk are unraveled, it becomes clear that this outstanding …

[HTML][HTML] Tuning the conformation and mechanical properties of silk fibroin hydrogels

N Johari, L Moroni, A Samadikuchaksaraei - European Polymer Journal, 2020 - Elsevier
Mechanical properties of biomaterials play an important role in their biological performance.
Among the most important parameters in designing of biomaterials, their structure and …

Semi-interpenetrating polymer network of hyaluronan and chitosan self-healing hydrogels for central nervous system repair

Y Liu, YH Hsu, APH Huang, S Hsu - ACS Applied Materials & …, 2020 - ACS Publications
The repair of the central nervous system (CNS) is a major challenge because of the difficulty
for neurons or axons to regenerate after damages. Injectable hydrogels have been …

Silk materials at the convergence of science, sustainability, healthcare, and technology

G Guidetti, L d'Amone, T Kim, G Matzeu… - Applied Physics …, 2022 - pubs.aip.org
Over the past few decades, Bombyx mori silk fibroin has become a ubiquitous material for
applications ranging from biomedical devices to optics, electronics, and sensing, while also …

[HTML][HTML] Delivery of miR-675 by stem cell-derived exosomes encapsulated in silk fibroin hydrogel prevents aging-induced vascular dysfunction in mouse hindlimb

C Han, J Zhou, B Liu, C Liang, X Pan, Y Zhang… - Materials Science and …, 2019 - Elsevier
Vascular disease is a major complication of aging, but the molecular mechanisms
underlying the aging-induced vascular dysfunction remain unclear, and there is no effective …

Skin-penetrating polymeric nanoparticles incorporated in silk fibroin hydrogel for topical delivery of curcumin to improve its therapeutic effect on psoriasis mouse …

KL Mao, ZL Fan, JD Yuan, PP Chen, JJ Yang… - Colloids and Surfaces B …, 2017 - Elsevier
A poor percutaneous penetration capability for most topical anti-inflammatory drugs is one of
the main causes compromising their therapeutic effects on psoriatic skin. Even though …

Self-assembled silk fibroin hydrogels: From preparation to biomedical applications

OC Onder, SR Batool, MA Nazeer - Materials Advances, 2022 - pubs.rsc.org
Silk fibroin (SF) from Bombyx mori silkworm has been used as a textile fiber for centuries. In
addition, for decades, SF has been used as a suture material. SF's unique properties, such …

Injectable ultrasonication-induced silk fibroin hydrogel for cartilage repair and regeneration

T Yuan, Z Li, Y Zhang, K Shen, X Zhang… - … Engineering Part A, 2021 - liebertpub.com
Articular cartilage lacks both a nutrient supply and progenitor cells. Once damaged, it has
limited self-repair capability. Cartilage tissue engineering provides a promising strategy for …

Composite silk fibroin hydrogel scaffolds for cartilage tissue regeneration

Z Montaseri, SS Abolmaali, AM Tamaddon… - Journal of Drug Delivery …, 2023 - Elsevier
Cartilage tissue engineering is becoming increasingly popular for repairing cartilage
defects. However, lack of nerves and blood vessels, as well as low cell density cause …

Biomaterial scaffolds in regenerative therapy of the central nervous system

Y Wang, H Tan, X Hui - BioMed research international, 2018 - Wiley Online Library
The central nervous system (CNS) is the most important section of the nervous system as it
regulates the function of various organs. Injury to the CNS causes impairment of …