Plasmids, a molecular cornerstone of antimicrobial resistance in the One Health era

S Castañeda-Barba, EM Top, T Stalder - Nature Reviews Microbiology, 2024 - nature.com
Antimicrobial resistance (AMR) poses a substantial threat to human health. The widespread
prevalence of AMR is, in part, due to the horizontal transfer of antibiotic resistance genes …

Epidemiology of β-lactamase-producing pathogens

K Bush, PA Bradford - Clinical microbiology reviews, 2020 - Am Soc Microbiol
SUMMARY β-Lactam antibiotics have been widely used as therapeutic agents for the past
70 years, resulting in emergence of an abundance of β-lactam-inactivating β-lactamases …

Mobile Carbapenemase Genes in Pseudomonas aeruginosa

EJ Yoon, SH Jeong - Frontiers in microbiology, 2021 - frontiersin.org
Carbapenem-resistant Pseudomonas aeruginosa is one of the major concerns in clinical
settings impelling a great challenge to antimicrobial therapy for patients with infections …

Klebsiella oxytoca complex: update on taxonomy, antimicrobial resistance, and virulence

J Yang, H Long, Y Hu, Y Feng… - Clinical microbiology …, 2022 - Am Soc Microbiol
Klebsiella oxytoca is actually a complex of nine species—Klebsiella grimontii, Klebsiella
huaxiensis, Klebsiella michiganensis, K. oxytoca, Klebsiella pasteurii, Klebsiella …

Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review

K Kopotsa, J Osei Sekyere… - Annals of the New York …, 2019 - Wiley Online Library
Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

Plasmid-mediated transfer of antibiotic resistance genes in soil

M Meng, Y Li, H Yao - Antibiotics, 2022 - mdpi.com
Due to selective pressure from the widespread use of antibiotics, antibiotic resistance genes
(ARGs) are found in human hosts, plants, and animals and virtually all natural environments …

Systematic detection of horizontal gene transfer across genera among multidrug-resistant bacteria in a single hospital

DR Evans, MP Griffith, AJ Sundermann, KA Shutt… - Elife, 2020 - elifesciences.org
Multidrug-resistant bacteria pose a serious health threat, especially in hospitals. Horizontal
gene transfer (HGT) of mobile genetic elements (MGEs) facilitates the spread of antibiotic …

Molecular Epidemiology of Carbapenemases in Enterobacteriales from Humans, Animals, Food and the Environment

G Taggar, M Attiq Rheman, P Boerlin, MS Diarra - Antibiotics, 2020 - mdpi.com
The Enterobacteriales order consists of seven families including Enterobacteriaceae,
Erwiniaceae, Pectobacteriaceae, Yersiniaceae, Hafniaceae, Morganellaceae, and …

Epidemiological Characteristics and Formation Mechanisms of Multidrug-Resistant Hypervirulent Klebsiella pneumoniae

M Tang, X Kong, J Hao, J Liu - Frontiers in microbiology, 2020 - frontiersin.org
Multi-drug resistance (MDR) and hypervirulence (hv) were exhibited by different well-
separated Klebsiella pneumoniae lineages in the past, but their convergence clones—MDR …

Carbapenem-Resistant Citrobacter spp. as an Emerging Concern in the Hospital-Setting: Results From a Genome-Based Regional Surveillance Study

Y Yao, L Falgenhauer, J Falgenhauer… - Frontiers in Cellular …, 2021 - frontiersin.org
The rise of Carbapenem-resistant Enterobacterales (CRE) represents an increasing threat to
patient safety and healthcare systems worldwide. Citrobacter spp., long considered not to be …