The immunology of long COVID

DM Altmann, EM Whettlock, S Liu… - Nature Reviews …, 2023 - nature.com
Long COVID is the patient-coined term for the disease entity whereby persistent symptoms
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …

Memory B and memory plasma cells

T Yoshida, H Mei, T Dörner, F Hiepe… - Immunological …, 2010 - Wiley Online Library
Vaccination provides a powerful means to control infections. It exploits and exemplifies the
ability of the immune system to preserve the information that a specific pathogen has been …

Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies

NA Doria-Rose, RM Klein, MM Manion, S O'Dell… - Journal of …, 2009 - Am Soc Microbiol
Induction of broadly cross-reactive neutralizing antibodies (NAb) is an important goal for a
prophylactic human immunodeficiency virus type 1 (HIV-1) vaccine. Some HIV-infected …

Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus

A Cappione, JH Anolik, A Pugh-Bernard… - The Journal of …, 2005 - Am Soc Clin Investig
Breach of B cell tolerance is central to the pathogenesis of systemic lupus erythematosus
(SLE). However, how B cell tolerance is subverted in human SLE is poorly understood due …

Selective dysregulation of the FcγIIB receptor on memory B cells in SLE

M Mackay, A Stanevsky, T Wang, C Aranow… - The Journal of …, 2006 - rupress.org
The inappropriate expansion and activation of autoreactive memory B cells and
plasmablasts contributes to loss of self-tolerance in systemic lupus erythematosus (SLE) …

Disruption of thrombocyte and T lymphocyte development by a mutation in ARPC1B

R Somech, A Lev, YN Lee, AJ Simon… - The Journal of …, 2017 - journals.aai.org
Regulation of the actin cytoskeleton is crucial for normal development and function of the
immune system, as evidenced by the severe immune abnormalities exhibited by patients …

Self-reactive VH4-34–expressing IgG B cells recognize commensal bacteria

JN Schickel, S Glauzy, YS Ng, N Chamberlain… - Journal of Experimental …, 2017 - rupress.org
The germline immunoglobulin (Ig) variable heavy chain 4–34 (VH4-34) gene segment
encodes in humans intrinsically self-reactive antibodies that recognize I/i carbohydrates …

Epstein-Barr virus-specific humoral immune responses in health and disease

JM Middeldorp - Epstein Barr Virus Volume 2: One Herpes Virus: Many …, 2015 - Springer
Epstein-Barr virus (EBV) is widely distributed in the world and associated with a still
increasing number of acute, chronic, malignant and autoimmune disease syndromes …

Epstein–Barr virus and systemic lupus erythematosus

JA James, JB Harley, RH Scofield - Current opinion in …, 2006 - journals.lww.com
This review will briefly outline the recent advances that show serologic, DNA, gene
expression, viral load, T cell responses, humoral fine specificity, and molecular mimicry …

[HTML][HTML] Hepatitis B virus-associated diffuse large B-cell lymphoma: unique clinical features, poor outcome, and hepatitis B surface antigen-driven origin

L Deng, Y Song, KH Young, S Hu, N Ding, W Song… - Oncotarget, 2015 - ncbi.nlm.nih.gov
While the epidemiologic association between hepatitis B virus (HBV) infection and diffuse
large B-cell lymphoma (DLBCL) is established, little is known more than this epidemiologic …