Preventing and controlling influenza virus infection remains a global public health
challenge, as it causes seasonal epidemics to unexpected pandemics. These infections are …

Virtual screening (VS) has emerged in drug discovery as a powerful computational
approach to screen large libraries of small molecules for new hits with desired properties …

Background: Virtual Screening (VS) has emerged as an important tool in the drug
development process, as it conducts efficient in silico searches over millions of compounds …

Background: The lengthy and expensive process of developing a novel medicine often takes
many years and entails a significant financial burden due to its poor success rate …

The high morbidity and mortality of cancer make it one of the leading causes of global death,
thus it is an urgent need to develop effective drugs for cancer therapy. Vascular endothelial …

Deficiency of the cholinergic system is thought to play a vital role in cognitive impairment of
dementia. DL0410 was discovered as a dual inhibitor of acetylcholinesterase (AChE) and …

High rates of drug failure cases are a challenge for the pharmaceutical industry to improve
preclinical testing. For the ADMET prediction, selection of suitable experimental data and its …

Influenza A virus (IAV) is a threat to public health due to its high mutation rate and resistance
to existing drugs. In this investigation, 15 targets selected from an influenza virus–host …

As the rate of discovery of new antibacterial compounds for multidrug-resistant bacteria is
declining, there is an urge for the search for molecules that could revert this tendency …

Drug design and drug discovery is a passionate, prolonged, and inter-disciplinary multistep
process. The traditional drug discovery process is costly and time-consuming which …