V Jannin, Y Cuppok - International journal of pharmaceutics, 2013 - Elsevier
Polymer coatings are widely used to provide drug protection, taste masking, coloration and modified drug release. Typically, coating polymers must be diluted or dispersed in solvents …
DG Lopes, S Salar-Behzadi, A Zimmer - International journal of …, 2017 - Elsevier
Hot-melt coating (HMC) as a solvent-free technology grants faster and more economic coating processes with reduced risk of dissolving the drug during the process. Moreover …
The present work investigates experimentally continuous spray fluidized bed layering with external product separation. In this process configuration, growing particles are continuously …
The present work investigates spray fluidized bed layering to continuously generate sodium benzoate granules from a solution. Product granules are discharged from the process …
DG Lopes, K Becker, M Stehr, D Lochmann… - Journal of …, 2015 - Elsevier
Hot-melt coating is of growing interest, because it does not require solvents, resulting in reduced process times and costs. However, excipients for this technology are mainly …
MG Müller, JA Lindner, H Briesen, K Sommer… - Advanced Powder …, 2018 - Elsevier
Coating of particulate solids is a well-known process within the chemical, pharmaceutical and food industry. Most of these industries use it to achieve a defined product behavior. Melt …
Y Yang, L Shen, J Li, W Shan - Drug Development and Industrial …, 2017 - Taylor & Francis
The objective of this study was to prepare and evaluate metoprolol tartrate sustained- release pellets. Cores were prepared by hot melt extrusion and coated pellets were …
A new first degree solids mixing rate is proposed to evaluate the mixing of solids in small scale fluidized beds. Particle mixing experiments were carried out in a 2D fluidized bed with …
B Zhang, N Kobayashi, Y Itaya - Powder Technology, 2019 - Elsevier
The combination of a spouted bed with non-thermal plasma has been used widely in industrial chemical processes. However, the detailed behavior of particles in a spouted bed …