Cigarette smoking, diabetes, and diabetes complications: call for urgent action
Abstract Purpose of Review This review aimed to examine the latest evidence linking
cigarette smoking and cessation to risk of incident diabetes and its complications. Recent …
cigarette smoking and cessation to risk of incident diabetes and its complications. Recent …
[HTML][HTML] Characterizing genetic and environmental influences on variable DNA methylation using monozygotic and dizygotic twins
Variation in DNA methylation is being increasingly associated with health and disease
outcomes. Although DNA methylation is hypothesized to be a mechanism by which both …
outcomes. Although DNA methylation is hypothesized to be a mechanism by which both …
[HTML][HTML] Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology
Most epigenome-wide association studies (EWAS) quantify DNA methylation (DNAm) in
peripheral tissues such as whole blood to identify positions in the genome where variation is …
peripheral tissues such as whole blood to identify positions in the genome where variation is …
[HTML][HTML] A prospective study of smoking-related white blood cell DNA methylation markers and risk of bladder cancer
Bladder cancer, a common neoplasm, is primarily caused by tobacco smoking. Epigenetic
alterations including DNA methylation have the potential to be used as prospective markers …
alterations including DNA methylation have the potential to be used as prospective markers …
[HTML][HTML] Cohort profile: Epigenetics in Pregnancy (EPIPREG)–population-based sample of European and South Asian pregnant women with epigenome-wide DNA …
N Fragoso-Bargas, JO Opsahl, N Kiryushchenko… - PLoS …, 2021 - journals.plos.org
Pregnancy is a valuable model to study the association between DNA methylation and
several cardiometabolic traits, due to its direct potential to influence mother's and child's …
several cardiometabolic traits, due to its direct potential to influence mother's and child's …
[HTML][HTML] Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking
Smoking-related epigenetic changes have been linked to lung cancer, but the contribution of
epigenetic alterations unrelated to smoking remains unclear. We sought for a sparse set of …
epigenetic alterations unrelated to smoking remains unclear. We sought for a sparse set of …
[HTML][HTML] Views of ophthalmologists on the genetics of age-related macular degeneration: results of a qualitative study
J Loss, D Müller, J Weigl, H Helbig, C Brandl, IM Heid… - PLoS …, 2018 - journals.plos.org
Background Age-related macular degeneration (AMD) is the leading cause of blindness in
industrialized countries. It is a multifactorial disease of the retina modified by environmental …
industrialized countries. It is a multifactorial disease of the retina modified by environmental …