Hyperlipidemia is a major risk factor for cardiovascular morbidity and mortality. Statins are
the first-choice therapy for dyslipidemias and are considered the cornerstone of …

SARS-CoV-2 infection is often associated with severe inflammation, oxidative stress,
hypoxia and impaired physical activity. These factors all together contribute to muscle …

COVID-19 disease is well documented and often the most common symptoms include
myalgia and muscle fatigue. Approximately 10% of those infected complain of persistent …

Acute bed rest places older adults at risk for health complications by disrupting homeostasis
in many organ systems, including the cardiovascular system. Circulating ceramides are …

Objectives Standard of care sepsis biomarkers such as C-reactive protein (CRP) and
procalcitonin (PCT) can be affected by several perinatal factors, among which perinatal …

The interplay between chronic constraint and advanced aging on blood flow, shear-rate,
vascular function, nitric oxide (NO)-bioavailability, microcirculation, and vascular …

The vascular endothelium is not only the semipermeable membrane that separates tissue
from blood but also an organ that regulates inflammation, vascular tone, blood clotting …

Hypokinesia triggers oxidative stress and accelerates the turnover of the glutathione system
via the γ-glutamyl cycle. Our study aimed to identify the regulatory checkpoints controlling …

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible
for coronavirus disease-2019 (COVID-19). Elderly subjects, obese, and patients with chronic …

Intrauterine growth-restricted (IUGR) fetuses exhibit systemic inflammation that contributes to
programmed deficits in myoblast function and muscle growth. Thus, we sought to determine …