Chromone, a privileged scaffold in drug discovery: Developments in the synthesis and bioactivity

AT Benny, SD Arikkatt, CG Vazhappilly… - Mini Reviews in …, 2022 - ingentaconnect.com
Chromones are the class of secondary metabolites that broadly occur in the plant kingdom
in a noticeable quantity. This rigid bicyclic system has been categorized “as privileged …

Health benefits of chromones: Common ingredients of our daily diet

RB Semwal, DK Semwal, S Combrinck… - Phytochemistry Reviews, 2020 - Springer
Chromones are naturally occurring phenolic compounds that are universally present in a
healthy human diet. To date, thousands of chromone derivatives, including chromone …

Bacterial cellulose nanocrystal as drug delivery system for overcoming the biological barrier of cyano-phycocyanin: a biomedical application of microbial product

HSH Munawaroh, B Anwar, G Yuliani, IC Murni… - …, 2023 - Taylor & Francis
Phycocyanin, produced by Spirulina platensis, has been reported as an anti-inflammatory,
anti-hyperalgesia, antioxidant, anti-tumor, and anti-cancer agent. However, the ingestion of …

Targeted Isolation of Anti-inflammatory Lignans from Justicia aequilabris by Molecular Networking Approach

JPR e Silva, LCO Pereira, LS Abreu… - Journal of Natural …, 2022 - ACS Publications
Herein, the isolation of secondary metabolites from the aerial parts of Justicia aequilabris
guided by HPLC-MS n and molecular networking analyses is reported. Twenty-two known …

Efficient synthesis and molecular docking studies of new pyrimidine-chromeno hybrid derivatives as potential antiproliferative agents

SÇ Yavuz, S Akkoç, B Tüzün, O Şahin… - Synthetic …, 2021 - Taylor & Francis
Various novel heterocyclic compounds containing pyrimidine nuclei 5 H-chromeno [4, 3-d]
pyrimidine (4a–c, e–h, l–r, t) and pyrimidine-5-yl-(2-hydroxyphenyl) methanone (5a, c, d, f–k …

[HTML][HTML] Preparation and characterization of C-phycocyanin coated with STMP/STPP cross-linked starches from different botanical sources

PVF Lemos, LCF Opretzka, LS Almeida… - International Journal of …, 2020 - Elsevier
This work aimed to use sodium trimetaphosphate/sodium tripolyphosphate cross-linked
potato, banana, corn, cassava, and breadfruit starches as wall materials for C-phycocyanin …

New chromones from the roots of Saposhnikovia divaricata (Turcz.) Schischk with anti-inflammatory activity

Y Sun, P Jiang, YK Jiang, J Pan, JT Wu, XM Li… - Bioorganic …, 2023 - Elsevier
Fifteen new chromones, sadivamones AE (1–5), cimifugin monoacetate (6), sadivamones
FN (7–15), together with fifteen known chromones (16–30), were isolated from the ethyl …

Synthesis of some new functionalized pyrano[2,3-c]pyrazoles and pyrazolo[4′,3′:5,6] pyrano[2,3-d]pyrimidines bearing a chromone ring as antioxidant agents

TE Ali, DA Bakhotmah, MA Assiri - Synthetic Communications, 2020 - Taylor & Francis
A new series of functionalized pyrano [2, 3-c] pyrazoles and pyrazolo [4′, 3′: 5, 6] pyrano
[2, 3-d] pyrimidines bearing a bioactive chromone ring was achieved. The methodology …

[HTML][HTML] Chromone-based small molecules for multistep shutdown of arachidonate pathway: Simultaneous inhibition of COX-2, 15-LOX and mPGES-1 enzymes

PA Elzahhar, R Orioli, NW Hassan, S Gobbi… - European Journal of …, 2024 - Elsevier
As a new approach to the management of inflammatory disorders, a series of chromone-
based derivatives containing a (carbamate) hydrazone moiety was designed and …

Synthesis, antimicrobial, antioxidant, tyrosinase inhibitory activities, and computational studies of novel chromen [2, 3-c] pyrazole derivatives

V Loganathan, A Mani, I Akbar, A Ahamed… - Molecular Diversity, 2024 - Springer
In this study, one-pot multicomponent reactions of novel chromeno [2, 3-c] pyrazole
derivatives (1–14) were performed using an AlCl 3 catalyst via cyclisation. Various spectral …