The changing epidemiology of invasive fungal infections

DA Enoch, H Yang, SH Aliyu, C Micallef - Human fungal pathogen …, 2017 - Springer
Invasive fungal infections (IFI) are an emerging problem worldwide with invasive candidiasis
and candidemia responsible for the majority of cases. This is predominantly driven by the …

Colonization by Pneumocystis jirovecii and its role in disease

A Morris, KA Norris - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Although the incidence of Pneumocystis pneumonia (PCP) has decreased since the
introduction of combination antiretroviral therapy, it remains an important cause of disease in …

A molecular window into the biology and epidemiology of Pneumocystis spp

L Ma, OH Cissé, JA Kovacs - Clinical microbiology reviews, 2018 - Am Soc Microbiol
Pneumocystis, a unique atypical fungus with an elusive lifestyle, has had an important
medical history. It came to prominence as an opportunistic pathogen that not only can cause …

Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity

M Kern, N Klöting, HG Niessen, L Thomas, D Stiller… - Plos one, 2012 - journals.plos.org
Linagliptin (tradjenta™) is a selective dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4
inhibition attenuates insulin resistance and improves peripheral glucose utilization in …

Invasive fungal diseases in Africa: a critical literature review

F Bongomin, BE Ekeng, W Kibone, L Nsenga, R Olum… - Journal of Fungi, 2022 - mdpi.com
Invasive fungal diseases (IFDs) are of huge concern in resource-limited settings, particularly
in Africa, due to the unavailability of diagnostic armamentarium for IFDs, thus making …

Global prevalence, mortality, and main characteristics of HIV-associated pneumocystosis: A systematic review and meta-analysis

E Ahmadpour, S Valilou, MA Ghanizadegan, R Seyfi… - Plos one, 2024 - journals.plos.org
The epidemiology of Human Immunodeficiency Virus (HIV)-associated pneumocystosis
(HAP) is poorly described on a worldwide scale. We searched related databases between …

Burden of serious fungal infections in Tanzania

D Faini, W Maokola, H Furrer, C Hatz, M Battegay… - Mycoses, 2015 - Wiley Online Library
The incidence and prevalence of fungal infections in Tanzania remains unknown. We
assessed the annual burden in the general population and among populations at risk. Data …

The prevalence of laboratory-confirmed Pneumocystis jirovecii in HIV-infected adults in Africa: A systematic review and meta-analysis

NK Wills, DS Lawrence, E Botsile… - Medical …, 2021 - academic.oup.com
Abstract Background: The epidemiology of Pneumocystis jirovecii, known to colonize the
respiratory tract and cause a life-threatening HIV-associated pneumonia (PCP), is poorly …

Etiologic diagnosis of lower respiratory tract bacterial infections using sputum samples and quantitative loop-mediated isothermal amplification

Y Kang, R Deng, C Wang, T Deng, P Peng, X Cheng… - PLoS …, 2012 - journals.plos.org
Etiologic diagnoses of lower respiratory tract infections (LRTI) have been relying primarily on
bacterial cultures that often fail to return useful results in time. Although DNA-based assays …

Detection of Pneumocystis jirovecii in oral wash from immunosuppressed patients as a diagnostic tool

CJ Hviid, M Lund, A Sørensen, S Ellermann-Eriksen… - PLoS …, 2017 - journals.plos.org
Background Diagnosis of Pneumocystis jirovecii (PJ) pneumonia ordinarily requires
invasive procedures that could be avoided by PCR methodologies, if these could be …