Several studies have shown that interleukin 6 (IL-6) is a multifunctional cytokine with both
pro-inflammatory and anti-inflammatory activity, depending on the immune response …

The S100 family of proteins contains 25 known members that share a high degree of
sequence and structural similarity. However, only a limited number of family members have …

Rare immune-mediated cardiac tissue inflammation can occur after vaccination, including
after SARS-CoV-2 mRNA vaccines. However, the underlying immune cellular and molecular …

Humans differ in their susceptibility to infectious disease, partly owing to variation in the
immune response after infection. We used single-cell RNA sequencing to quantify variation …

Cystic fibrosis (CF) is a lethal autosomal recessive disorder that afflicts more than 70,000
people. People with CF experience multi-organ dysfunction resulting from aberrant …

Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Psychosocial stress has profound effects on the body, including the immune system and the
brain,. Although a large number of pre-clinical and clinical studies have linked peripheral …

Simple Summary Since the targeting of a single pro-angiogenic factor fails to improve
oncological disease outcome, significant efforts have been made to identify new pro …

T cell-centric immunotherapies have shown modest clinical benefit thus far for estrogen
receptor-positive (ER+) breast cancer. Despite accounting for 70% of all breast cancers …

COVID-19 is characterized by dysregulated thrombosis and coagulation that can increase
mortality in patients. Platelets are fast responders to pathogen presence, alerting the …