A Coulon - Current Opinion in Genetics & Development, 2025 - Elsevier
The physical organization and properties of chromatin within the interphase nucleus are intimately linked to a wide range of functional DNA-based processes. In this context …
NA Fursova, DR Larson - Current Opinion in Structural Biology, 2024 - Elsevier
Chromatin organization, facilitated by compartmentalization and loop extrusion, is crucial for proper gene expression and cell viability. Transcription has long been considered important …
VY Goel, NG Aboreden, JM Jusuf, H Zhang, LP Mori… - BioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
As cells exit mitosis and enter G1, mitotic chromosomes decompact and transcription is reestablished. Previously, Hi-C studies showed that essentially all interphase 3D genome …
Z Cao, PG Wolynes - The Journal of Chemical Physics, 2024 - pubs.aip.org
Chromatin is partially structured through the effects of biological motors.“Swimming motors” such as RNA polymerases and chromatin remodelers are thought to act differentially on the …
R Riera Aroche, YM Ortiz García… - Current issues in …, 2024 - mdpi.com
Previously, we described that Adenine, Thymine, Cytosine, and Guanine nucleobases were superconductors in a quantum superposition of phases on each side of the central hydrogen …
P Singh, J Serizay, J Couble, MD Cabahug, C Rosa… - bioRxiv, 2024 - biorxiv.org
Genome organization plays a significant role in silencing heterochromatinized genes in the most virulent human malaria parasite, Plasmodium falciparum. However, it remains unclear …
K Roychoudhury, S Pande, IS Shashank… - arXiv preprint arXiv …, 2025 - arxiv.org
It has been shown that under high cylindrical confinement, two ring polymers with excluded volume interactions between monomers, segregate to two halves of the cylinder to maximize …
M Rey-Millet, K Bystricky… - 2024 - Taylor & Francis
ABSTRACT DNA sequencing is not enough to grasp the complexity of genome organization and function. The four-dimensional (three in space, one in time) configuration of the …
V Piveteau, H Salari, A Dumont, J Savocco, C Dupont… - bioRxiv, 2024 - biorxiv.org
The in vivo mechanism, regulations by cis-acting roadblocks, and biological functions of loop extrusion by eukaryotic SMC complexes are incompletely defined. Here, using Hi-C, we …