Eosinophils from A to Z

L Gigon, T Fettrelet, S Yousefi, D Simon, HU Simon - Allergy, 2023 - Wiley Online Library
Eosinophils are bone marrow‐derived granulocytes and are found in low numbers in the
peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the …

Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease

IC Arnold, A Munitz - Nature Reviews Immunology, 2024 - nature.com
Eosinophils are bone marrow-derived granulocytes that are traditionally associated with
type 2 immune responses, such as those that occur during parasite infections and allergy …

Eosinophils as potential biomarkers in respiratory viral infections

I Macchia, V La Sorsa, F Urbani, S Moretti… - Frontiers in …, 2023 - frontiersin.org
Eosinophils are bone marrow-derived granulocytes that, under homeostatic conditions,
account for as much as 1-3% of peripheral blood leukocytes. During inflammation …

Immunopathologic role of fungi in chronic rhinosinusitis

SH Shin, MK Ye, DW Lee, SY Geum - International Journal of Molecular …, 2023 - mdpi.com
Airborne fungi are ubiquitous in the environment and are commonly associated with airway
inflammatory diseases. The innate immune defense system eliminates most inhaled fungi …

2B4: A potential target in Staphylococcus aureus associated allergic inflammation

P Gaur, M Seaf, N Trabelsi, O Marcu… - Clinical and …, 2024 - academic.oup.com
Staphylococcus aureus (SA) and its exotoxins activate eosinophils (Eos) and mast cells
(MCs) via CD48, a GPI-anchored receptor belonging to the signaling lymphocytes activation …

In vivo single-cell high-dimensional mass cytometry analysis to track the interactions between Klebsiella pneumoniae and myeloid cells

R Calderon-Gonzalez, A Dumigan, J Sá-Pessoa… - PLoS …, 2024 - journals.plos.org
In vivo single-cell approaches have transformed our understanding of the immune
populations in tissues. Mass cytometry (CyTOF), that combines the resolution of mass …

Blood heparin-binding protein and neutrophil-to-lymphocyte ratio as indicators of the severity and prognosis of community-acquired pneumonia

Y Meng, L Zhang, M Huang, G Sun - Respiratory Medicine, 2023 - Elsevier
Background Community-acquired pneumonia (CAP) is particularly prevalent and has high
mortality in severely ill patients, but the role of current biomarkers is limited. This study aimed …

Eosinophil activation during immune responses: an ultrastructural view with an emphasis on viral diseases

RCN Melo, TP Silva - Journal of Leukocyte Biology, 2024 - academic.oup.com
Eosinophils are cells of the innate immune system that orchestrate complex inflammatory
responses. The study of the cell biology of eosinophils, particularly associated with cell …

Eosinophils in Colorectal Cancer: Emerging Insights into Anti-Tumoral Mechanisms and Clinical Implications

D Lopez-Perez, B Prados-Lopez, J Galvez… - International Journal of …, 2024 - mdpi.com
Eosinophils are myeloid effector cells whose main homing is the gastrointestinal tract. There,
they take part in type I and type II immune responses. They also contribute to other non …

[HTML][HTML] Does Eosinophil Heterogeneity Translate into Functional Diversity? A Review of the Evolving Paradigm of Eosinophil Heterogeneity in Asthma

GE Wilson, S Gautam, GL Chupp - Biomedicines, 2024 - mdpi.com
This review provides an overview of evidence supporting the existence of distinct
homeostatic and inflammatory eosinophil subpopulations in health and disease. Particular …