Background Cholangiocarcinomas are a heterogeneous group of malignancies arising from
a number of cells of origin along the biliary tree. Although most cases in Western countries …

Improved detection and characterization of common focal liver lesions (FLL) are the main
topics of the World Federation for Ultrasound in Medicine and Biology (WFUMB) guidelines …

The advent of enhanced radiological imaging techniques has facilitated the diagnosis of
cystic liver lesions. Concomitantly, the evidence base supporting the management of these …

Simple Summary Intrahepatic cholangiocarcinoma (ICCA) is the second most common type
of primary liver malignancy after hepatocellular carcinoma (HCC). ICCA is characterized by …

Intrahepatic cholangiocarcinoma (iCCA) is a rare neoplasm of the bile ducts with a low
survival rate, whose incidence is continuously increasing and is associated with a rich and …

Fibropolycystic liver diseases (FLDs) make up a rare spectrum of heritable hepatobiliary
diseases resulting from congenital ductal plate malformations (DPMs) due to the dysfunction …

Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive malignant neoplasm. Certain
histologic features and the tumor microenvironment may impact disease progression. We …

Aim There is some evidence that von Meyenburg complexes (VMCs) can progress to
cholangiocarcinoma (CC). This study aimed to evaluate the prevalence of VMCs in CC …

The aim of the present study was to evaluate the expression and specific role of microRNA
(miR)‑142‑5p in the progression of intrahepatic cholangiocarcinoma (ICC). Reverse …

The Notch signaling pathway plays a key role in the morphogenesis of the biliary tree, but its
involvement in cystic biliary diseases, such as Caroli disease (CD) and polycystic liver …