Kaposiform hemangioendothelioma: current knowledge and future perspectives

Y Ji, S Chen, K Yang, C Xia, L Li - Orphanet journal of rare diseases, 2020 - Springer
Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm with high morbidity
and mortality. The initiating mechanism during the pathogenesis of KHE has yet to be …

Sirolimus plus prednisolone vs sirolimus monotherapy for kaposiform hemangioendothelioma: a randomized clinical trial

Y Ji, S Chen, J Zhou, K Yang, X Zhang… - Blood, The Journal …, 2022 - ashpublications.org
Abstract The Kasabach-Merritt phenomenon (KMP) in kaposiform hemangioendothelioma
(KHE) is characterized by life-threatening thrombocytopenia and consumptive coagulopathy …

Long‐term outcomes of sirolimus treatment for kaposiform hemangioendothelioma: Continuing successes and ongoing challenges

J Zhou, Y Li, T Qiu, X Gong, K Yang… - … Journal of Cancer, 2023 - Wiley Online Library
Abstract Treatment with sirolimus, an inhibitor of the mammalian target of rapamycin
pathway, has improved the prognosis of patients with kaposiform hemangioendothelioma …

Sirolimus for kaposiform hemangioendothelioma: Potential mechanisms of action and resistance

T Qiu, S Xiang, J Zhou, M Yang, Y Lan… - … Journal of Cancer, 2025 - Wiley Online Library
Kaposiform hemangioendotheliomas (KHEs) are vascular tumors that are considered
borderline or locally aggressive and may lead to lethal outcomes. Traditional therapies, such …

Kaposiform lymphangiomatosis and kaposiform hemangioendothelioma: similarities and differences

Y Ji, S Chen, S Peng, C Xia, L Li - Orphanet Journal of Rare Diseases, 2019 - Springer
Background Kaposiform lymphangiomatosis (KLA) and kaposiform hemangioendothelioma
(KHE) are rare and aggressive vascular disorders. The aim of this study was to examine the …

Case report: kaposiform hemangioendothelioma with spinal involvement

T Qiu, K Yang, S Dai, S Chen, Y Ji - Frontiers in Pediatrics, 2021 - frontiersin.org
Introduction: Kaposiform hemangioendothelioma (KHE) is a rare, locally invasive vascular
tumor that mostly appears in infants and adolescents. KHE with spinal involvement is …

[PDF][PDF] Rare adult Kaposiform hemangioendothelioma with multiple-bone invasion—Clinical experience and literature review

J Xing, N Zhang, B Chen, ZC Tong… - Eur. Rev. Med …, 2023 - europeanreview.org
BACKGROUND: Kaposiform hemangioendothelioma (KHE) is a borderline vascular tumor
between hemangioma and malignant angiosarcoma. While KHE has strong local invasion …

Tacrolimus ointment for the treatment of superficial kaposiform hemangioendothelioma and tufted angioma

X Zhang, K Yang, S Chen, Y Ji - The Journal of Dermatology, 2019 - Wiley Online Library
Kaposiform hemangioendothelioma (KHE) and tufted angioma (TA) are rare infiltrative
vascular tumors. Currently, no standard treatment regimens exist for KHE/TA. The purpose of …

Health-related quality of life in children with kaposiform hemangioendothelioma

S Dai, K Yang, T Qiu, J Zhou, X Zhang, S Chen… - Frontiers in …, 2022 - frontiersin.org
Background and Objective Kaposiform hemangioendothelioma (KHE) is a rare, aggressive
and borderline vascular tumor mainly occurring in infants and children. The aim of this study …

Kaposiform hemangioendothelioma presented with raynaud phenomenon: a case report

L Liu, W Gu, L Teng, Y Xu, F Zheng, M Hu, M Lu, X Xu - BMC pediatrics, 2023 - Springer
Background Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm
affecting infants or young children. KHE includes a spectrum of lesions, ranging from small …