Interactions between nanoparticles and intestine

M Vitulo, E Gnodi, R Meneveri, D Barisani - International Journal of …, 2022 - mdpi.com
The use of nanoparticles (NPs) has surely grown in recent years due to their versatility, with
a spectrum of applications that range from nanomedicine to the food industry. Recent …

Oral drug delivery vehicle for insulin and curcumin based on egg albumin-dextran conjugate: In vitro and in vivo studies

AA Sayed, MMA Moteleb, E El Shafee… - Journal of Drug Delivery …, 2024 - Elsevier
The increasing desire for oral delivery vehicle systems encouraged the development of
micro and nano encapsulation technologies to protect drugs against gastric and enzymatic …

Molecular prospect of type-2 diabetes: Nanotechnology based diagnostics and therapeutic intervention

RG Kerry, GP Mahapatra, GK Maurya, S Patra… - Reviews in Endocrine …, 2021 - Springer
About ninety percent of all diabetic conditions account for T2D caused due to abnormal
insulin secretion/action or increased hepatic glucose production. Factors that contribute …

Nanophytosomes for enhancement of rutin efficacy in oral administration for diabetes treatment in streptozotocin-induced diabetic rats

S Amjadi, F Shahnaz, B Shokouhi, Y Azarmi… - International journal of …, 2021 - Elsevier
Rutin is a natural antioxidant compound with several therapeutic benefits. However, the
application of this bioactive compound is limited due to its low stability and bioavailability. To …

Synthesis and antidiabetic properties of chitosan-stabilized selenium nanoparticles

S Zeng, Y Ke, Y Liu, Y Shen, L Zhang, C Li, A Liu… - Colloids and Surfaces B …, 2018 - Elsevier
Chitosan-stabilized selenium nanoparticles (CTS-SeNPs) were prepared through the
reduction of selenite acid with ascorbic acid. The optimal synthesis conditions of CTS …

Enhancement of therapeutic efficacy of betanin for diabetes treatment by liposomal nanocarriers

S Amjadi, MM Abbasi, B Shokouhi, M Ghorbani… - Journal of functional …, 2019 - Elsevier
Betanin is a bioactive compound with a high antioxidant activity and therapeutic potential.
However, incomplete oral absorption and low stability of betanin limit its application. To …

Glucose-responsive hydrogel enhances the preventive effect of insulin and liraglutide on diabetic nephropathy of rats

MQ Tong, LZ Luo, PP Xue, YH Han, LF Wang… - Acta Biomaterialia, 2021 - Elsevier
Diabetic nephropathy (DN) is one of the most serious complications of diabetes mellitus. The
combination of insulin (Ins) with liraglutide (Lir) has a greater potential for preventing DN …

Comprehensive review on polymeric and metal nanoparticles: Possible therapeutic avenues

R Thakur, V Arora - … Journal of Polymeric Materials and Polymeric …, 2023 - Taylor & Francis
The current scenario has seen many transformative changes in target-based drug delivery
system. In this direction, encapsulation of medicines in nanoparticles has almost …

[PDF][PDF] Investigation of the antioxidant defensive role of both AD-MSCs and BM-MSCs in modulating the alteration in the oxidative stress status in various STZ-diabetic …

SG El-Sawah, F Althobaiti, A Aldhahrani, E Fayad… - Biocell, 2021 - cdn.techscience.cn
Diabetes mellitus (DM) could negatively affect patients' health via inducing a lot of serious
functional hazards in many tissues' cells at molecular levels. Recently, many scientists had …

Current status and applications of animal models in pre-clinical development of orally administered insulin-loaded nanoparticles

CY Wong, H Al-Salami, CR Dass - Journal of Drug Targeting, 2020 - Taylor & Francis
Oral delivery of insulin-loaded therapeutics is challenging due to the extreme pH condition,
enzymatic degradation, and limited permeation in the gastrointestinal (GI) tract …