Pro-protein convertase subtilisin/kexin type 9 (PCSK9) is secreted mostly by hepatocytes
and to a lesser extent by the intestine, pancreas, kidney, adipose tissue, and vascular cells …

Autosomal dominant familial hypercholesterolemia (FH) affects approximately 1/250,
individuals and potentially leads to elevated blood cholesterol and a significantly increased …

Erectile dysfunction (ED) can be caused by different diseases and controlled by several
genetic networks. In this study, to identify the genes related to ED, the expression profiles of …

Loss-of-function variants in PCSK9 (proprotein convertase subtilisin-kexin type 9) are
associated with lower lifetime risk of atherosclerotic cardiovascular disease) events …

Background: Coronary artery disease (CAD) is a chronic, inflammatory, and complex
disease associated with vascular risk factors. Nowadays, the coronary artery calcium (CAC) …

Introduction Proprotein convertase subtilisin/kexin type 9 (PCSK9) genetic polymorphisms
play a significant role in cholesterol homeostasis. Therefore, we aimed to investigate the …

Objective The effect of hypolipidemic drugs on male erectile function is still controversial.
This Mendelian randomization (MR) study aimed to explore the potential impact of lipid …

The increase in carotid intima-media thickness (CIMT) and coronary artery calcification
(CAC) are features of subclinical atherosclerosis that might be determined by the genetic …

This study is aimed at investigating the correlations of PCSK9 and LDLR gene
polymorphisms as well as serum proprotein convertase subtilisin/kexin type 9 (PCSK9) …

Erectile dysfunction (ED) is one of the most common sexual disorders in men. During the
past 30 years, there has been no new drug development for ED. Thus, exploring the genetic …