The Molecular Architecture of Pseudomonas aeruginosa Quorum-Sensing Inhibitors

Q Li, S Mao, H Wang, X Ye - Marine Drugs, 2022 - mdpi.com
The survival selection pressure caused by antibiotic-mediated bactericidal and bacteriostatic
activity is one of the important inducements for bacteria to develop drug resistance. Bacteria …

Chemical probe of AHL modulators on quorum sensing in Gram-Negative Bacteria and as antiproliferative agents: A review

M Ampomah-Wireko, C Luo, Y Cao, H Wang… - European Journal of …, 2021 - Elsevier
Pathogenic bacteria use an intercellular chemical communication system called quorum
sensing (QS) to control the expression of cellular functions such as virulence factors, biofilm …

Quorum Sensing Inhibitory and Quenching Activity of Bacillus cereus RC1 Extracts on Soft Rot-Causing Bacteria Lelliottia amnigena

R Kachhadia, C Kapadia, S Singh, K Gandhi… - ACS …, 2022 - ACS Publications
The quorum sensing (QS) system of bacteria helps them to communicate with each other in
a density-dependent manner and regulates pathogenicity. The concentrations of …

Pseudomonas aeruginosa inhibits quorum-sensing mechanisms of soft rot pathogen Lelliottia amnigena RCE to regulate its virulence factors and biofilm formation

C Kapadia, R Kachhdia, S Singh, K Gandhi… - Frontiers in …, 2022 - frontiersin.org
The quorum-sensing (QS) cascade is responsible for the colonization and phenotypic
behavior of the pathogenic organism and the regulation of diverse signal molecules. The …

Dihydropyrrolones as bacterial quorum sensing inhibitors

B Almohaywi, TT Yu, G Iskander, DSH Chan… - Bioorganic & Medicinal …, 2019 - Elsevier
Bacteria regulate their pathogenicity and biofilm formation through quorum sensing (QS),
which is an intercellular communication system mediated by the binding of signaling …

Thioether-linked dihydropyrrol-2-one analogues as PqsR antagonists against antibiotic resistant Pseudomonas aeruginosa

S Sabir, D Suresh, S Subramoni, T Das… - Bioorganic & medicinal …, 2021 - Elsevier
The Pseudomonas quinolone system (pqs) is one of the key quorum sensing systems in
antibiotic-resistant P. aeruginosa and is responsible for the production of virulence factors …

Investigating the Mechanism of Action of Diketopiperazines Inhibitors of the Burkholderia cenocepacia Quorum Sensing Synthase CepI: A Site-Directed Mutagenesis …

S Buroni, VC Scoffone, M Fumagalli… - Frontiers in …, 2018 - frontiersin.org
Quorum sensing (QS) is a bacterial intercellular communication process which controls the
production of major virulence factors, such as proteases, siderophores, and toxins, as well …

Synthetic homoserine lactone analogues as antagonists of bacterial quorum sensing

X Qin, GK Thota, R Singh, R Balamurugan… - Bioorganic …, 2020 - Elsevier
Quorum sensing (QS) is a density-dependent form of cell-cell communication that triggers
the functional coordination of cooperative behaviors such as the production of virulence …

Molecular docking, and anti-biofilm activity of gold-complexed sulfonamides on Pseudomonas aeruginosa

CR Mizdal, ST Stefanello, PA Nogara, FAA Soares… - Microbial …, 2018 - Elsevier
The antibacterial activity of sulfadiazine Au-PPh 3, sulfadiazine Ph 2 P-Au-Au-PPh 2,
sulfamethoxazole Au-PPh 3, sulfamethoxazole Ph 2 P-Au-Au-PPh 2, sulfamethoxazole Au …

A comprehensive review on structural attributes of biofilm inhibitors against potential targets

MR Borkar, K Khade, A Sherje - Journal of Molecular Structure, 2023 - Elsevier
Bacterial infections are among the world's most significant public health problems due to
their growing resistant to the majority of existing antibiotics and associated with increase in …