The use of antibiotics has enabled the successful treatment of bacterial infections, saving the
lives and improving the health of many patients worldwide. However, the emergence and …

With the advent of next-generation sequencing, we have an unprecedented ability to study
tumor and host genomes as well as those of the vast array of microorganisms that exist …

Background Current therapies for recurrent Clostridioides difficile infection do not address
the disrupted microbiome, which supports C. difficile spore germination into toxin-producing …

The gut microbiota has an important role in the maintenance of human health and in disease
pathogenesis. This importance was realized through the advent of omics technologies and …

Faecal microbiota transplantation (FMT) is an important therapeutic option for Clostridium
difficile infection. Promising findings suggest that FMT may play a role also in the …

Developments in high-throughput microbial genomic sequencing and other systems biology
techniques have given novel insight into the potential contribution of the gut microbiota to …

Gut microbiota have important functions in the body, and imbalances in the composition and
diversity of those microbiota can cause several diseases. The host fosters favorable …

The intestinal milieu harbours the gut microbiota, consisting of a complex community of
bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an …

The capability to design microbiomes with predictable functions would enable new
technologies for applications in health, agriculture, and bioprocessing. Towards this goal …

Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …