Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …

Subsets of mammalian adult stem cells reside in the quiescent state for prolonged periods of
time. This state, which is reversible, has long been viewed as dormant and with minimal …

The annual regrowth of deer antlers provides a valuable model for studying organ
regeneration in mammals. We describe a single-cell atlas of antler regrowth. The earliest …

Self‐healing is a natural process common to all living organisms which provides increased
longevity and the ability to adapt to changes in the environment. Inspired by this fitness …

The failure to replace damaged body parts in adult mammals results from a muted growth
response and fibrotic scarring. Although infiltrating immune cells play a major role in …

Cellular plasticity contributes to the regenerative capacity of plants, invertebrates, teleost
fishes and amphibians. In vertebrates, differentiated cells are known to revert into replicating …

Burn injury is a severe form of trauma affecting more than 2 million people in North America
each year. Burn trauma is not a single pathophysiological event but a devastating injury that …

The repair of wounds is one of the most complex biological processes that occur during
human life. After an injury, multiple biological pathways immediately become activated and …

Following a skin injury, the damaged tissue is repaired through the coordinated biological
actions that constitute the cutaneous healing response. In mammals, repaired skin is not …

Chargé, Sophie BP, and Michael A. Rudnicki. Cellular and Molecular Regulation of Muscle
Regeneration. Physiol Rev 84: 209–238, 2004; 10.1152/physrev. 00019.2003.—Under …