During development and throughout adult life, macrophages derived from hematopoietic
progenitors are seeded throughout the body, initially in the absence of inflammatory and …

BACKGROUND Infection and inflammation of the reproductive tract are significant causes of
male factor infertility. Ascending infections caused by sexually transmitted bacteria or urinary …

Throughout embryonic and early postnatal development, the mammalian epididymis
changes from a straight tube to a highly coiled, complex duct that links the efferent ducts to …

This chapter explores the possibility that capacitation and apoptosis are linked processes
joined by their common dependence on the continued generation of reactive oxygen …

Imaging reveals complex structures and dynamic interactive processes, located deep inside
the body, that are otherwise difficult to decipher. Numerous imaging modalities harness …

The ability of spermatogenic cells to evade the host immune system and the ability of
systemic inflammation to inhibit male reproductive function represent two of the most …

The male genital tract (MGT) is the target of a number of viral infections that can have
deleterious consequences at the individual, offspring, and population levels. These …

BACKGROUND Spermatozoa acquire their motility and fertilizing abilities during their
maturation through the epididymis. This process is controlled by epididymal epithelial cells …

Epithelial cells line the lumen of tubular organs and are key players in their respective
functions. They establish a unique luminal environment by providing a protective barrier and …

The epididymis is responsible for post-testicular sperm maturation, which consists in the
acquisition of forward motility and fertilizing ability. This organ is composed of three main …