Restricting retrotransposons: a review

JL Goodier - Mobile DNA, 2016 - Springer
Retrotransposons have generated about 40% of the human genome. This review examines
the strategies the cell has evolved to coexist with these genomic “parasites”, focussing on …

Ionizing radiation-induced epigenetic modifications and their relevance to radiation protection

M Belli, MA Tabocchini - International journal of molecular sciences, 2020 - mdpi.com
The present system of radiation protection assumes that exposure at low doses and/or low
dose-rates leads to health risks linearly related to the dose. They are evaluated by a …

Adaptation to global change: a transposable element–epigenetics perspective

O Rey, E Danchin, M Mirouze, C Loot… - Trends in ecology & …, 2016 - cell.com
Understanding how organisms cope with global change is a major scientific challenge. The
molecular pathways underlying rapid adaptive phenotypic responses to global change …

The important contribution of transposable elements to phenotypic variation and evolution

NS Catlin, EB Josephs - Current opinion in plant biology, 2022 - Elsevier
Transposable elements (TEs) are responsible for significant genomic variation in plants. Our
understanding of the evolutionary forces shaping TE polymorphism has lagged behind other …

Effects of ionizing radiation on DNA methylation: from experimental biology to clinical applications

IR Miousse, KR Kutanzi, I Koturbash - International journal of …, 2017 - Taylor & Francis
Purpose: Ionizing radiation (IR) is a ubiquitous environmental stressor with genotoxic and
epigenotoxic capabilities. Terrestrial IR, predominantly a low-linear energy transfer (LET) …

Ionizing radiation and human health: Reviewing models of exposure and mechanisms of cellular damage. An epigenetic perspective

E Burgio, P Piscitelli, L Migliore - International journal of environmental …, 2018 - mdpi.com
We reviewed available evidence in medical literature concerning experimental models of
exposure to ionizing radiations (IR) and their mechanisms of producing damages on living …

Epigenetically facilitated mutational assimilation: epigenetics as a hub within the inclusive evolutionary synthesis

E Danchin, A Pocheville, O Rey, B Pujol… - Biological …, 2019 - Wiley Online Library
After decades of debate about the existence of non‐genetic inheritance, the focus is now
slowly shifting towards dissecting its underlying mechanisms. Here, we propose a new …

Stress-driven transposable element de-repression dynamics and virulence evolution in a fungal pathogen

S Fouché, T Badet, U Oggenfuss… - Molecular biology …, 2020 - academic.oup.com
Transposable elements (TEs) are drivers of genome evolution and affect the expression
landscape of the host genome. Stress is a major factor inducing TE activity; however, the …

Transposable elements potentiate radiotherapy-induced cellular immune reactions via RIG-I-mediated virus-sensing pathways

J Du, SI Kageyama, R Yamashita, K Tanaka… - Communications …, 2023 - nature.com
Radiotherapy (RT) plus immunotherapy is a promising modality; however, the therapeutic
effects are insufficient, and the molecular mechanism requires clarification to further develop …

Physiological mechanisms of stress-induced evolution

EA Mojica, D Kültz - Journal of Experimental Biology, 2022 - journals.biologists.com
Organisms mount the cellular stress response whenever environmental parameters exceed
the range that is conducive to maintaining homeostasis. This response is critical for survival …