Surface proteoglycans as mediators in bacterial pathogens infections

B García, J Merayo-Lloves, C Martin, I Alcalde… - Frontiers in …, 2016 - frontiersin.org
Infectious diseases remain an important global health problem. The interaction of a wide
range of pathogen bacteria with host cells from many different tissues is frequently mediated …

Heparin, heparan sulphate and sepsis: potential new options for treatment

J Hogwood, E Gray, B Mulloy - Pharmaceuticals, 2023 - mdpi.com
Sepsis is a life-threatening hyperreaction to infection in which excessive inflammatory and
immune responses cause damage to host tissues and organs. The glycosaminoglycan …

Highly efficient multivalent 2D nanosystems for inhibition of orthopoxvirus particles

B Ziem, H Thien, K Achazi, C Yue… - Advanced …, 2016 - Wiley Online Library
Efficient inhibition of cell–pathogen interaction to prevent subsequent infection is an urgent
but yet unsolved problem. In this study, the synthesis and functionalization of novel …

Semi-synthesis of N-alkyl-kappa-carrageenan derivatives and evaluation of their antibacterial activity

EH Júnior, AG Gonçalves, MD Noseda… - Carbohydrate …, 2021 - Elsevier
In this article, we describe the semi-synthesis of N-alkyl-kappa-carrageenan derivatives and
their antibacterial activity against Staphylococcus aureus (ATCC 6538), Escherichia coli …

[HTML][HTML] Recent innovations in the structural analysis of heparin

EA Yates, TR Rudd - International journal of cardiology, 2016 - Elsevier
Heparin, the widely used anticoagulant drug, is unusual among major pharmaceutical
agents being neither single chemical entity nor a defined mixture of compounds. Its …

Pentamethinium salts as ligands for cancer: Sulfated polysaccharide co-receptors as possible therapeutic target

T Bříza, J Králová, S Rimpelová, M Havlík… - Bioorganic …, 2019 - Elsevier
A series of pentamethinium salts with benzothiazolium and indolium side units comprising
one or two positive charges were designed and synthesized to determine the relationships …

Characterization of Viral inhibiting 2D Carbon-based structures using Scanning Probe Microscopy and Raman Spectroscopy

MFF Gholami - 2023 - search.proquest.com
The activity of matter can be ascribed to a system, consisting of individually active
components, which exhibit a collective behavior. Multivalent interactions are common in the …

[PDF][PDF] Studies on the effects of sulfated polysaccharides on malaria infection

FC Recuenco - (No Title), 2014 - repository.dl.itc.u-tokyo.ac.jp
Malaria is one of the most significant parasitic diseases in the world. Even with increased
efforts focused on controlling the protozoan parasites as well as the mosquito vector, malaria …