Symptoms of neurological diseases emerge through the dysfunction of neural circuits whose
diffuse and intertwined architectures pose serious challenges for delivering therapies. Deep …

Dystonia is a debilitating disease with few treatment options. One effective option is deep
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …

Objective Deep brain stimulation (DBS) has considerable efficacy for the motor dysfunction
of idiopathic Parkinson's disease (PD) on patient quality of life. However, the benefit of DBS …

Magnetic resonance-guided focused ultrasound (MRgFUS) is a novel and minimally
invasive technology. Since the US Food and Drug Administration approved unilateral ventral …

Globus pallidus internus deep brain stimulation is an established therapy for patients with
medication-refractory Parkinson's disease. Clinical outcomes are highly dependent on …

Objective The subthalamic nucleus (STN) and internal globus pallidus (GPi) are the most
effective targets in deep brain stimulation (DBS) for Parkinson's disease (PD). However, the …

Parkinson's disease can be associated with significant cognitive impairment that may lead to
dementia. Deep brain stimulation (DBS) of the subthalamic nucleus is an effective therapy …

Background Deep brain stimulation (DBS) devices with neural recording capabilities are
commercially available and may potentially improve clinical care and advance research …

OBJECTIVE Functional MRI (fMRI) has been used to investigate the therapeutic
mechanisms underlying deep brain stimulation (DBS) for Parkinson's disease (PD) …

Deep brain stimulation (DBS) is a very well-established and effective treatment for patients
with extrapyramidal diseases. Despite its generally favorable clinical efficacy, some …