The aspergilli comprise a diverse group of filamentous fungi spanning over 200 million
years of evolution. Here we report the genome sequence of the model organism Aspergillus …

Aspergilli represent unique pathogens. Based on their saprophytic life style they are able to
colonize a variety of ecological niches, among them the immunocompromised individual …

Because some metabolic intermediates are involved in more than one pathway, crosstalk
between pathways is crucial to maintaining homeostasis. AMP and histidine biosynthesis …

The CPCA protein of the filamentous fungus Aspergillus nidulans is a member of the c-Jun-
like transcriptional activator family. It acts as central transcription factor of the cross-pathway …

New antimycotic drugs are challenging to find, as potential target proteins may have close
human orthologs. We here focus on identifying metabolic targets that are critical for fungal …

A combined proteomics and metabolomics approach was utilised to advance the
identification and characterisation of secondary metabolites in Aspergillus fumigatus. Here …

Sexual development is the classical parameter for the taxonomical classification of animals,
plants, and fungi. This is reflected in the nomenclature of numerous taxons of the fungal …

Developmental biology, which deals with the various aspects of species-specific changes
during the lifetime of individuals, is central to the biological sciences and connects the …

The fifth step of histidine biosynthesis is catalysed by an imidazole glycerol-phosphate (IGP)
synthase. In Archaea and Bacteria, the active form of IGP synthase is a stable 1: 1 dimeric …

The non-proteinogenic amino acid, α-aminoadipate, defines the biosynthetic branch-point of
lysine and penicillin biosynthesis in the filamentous fungus, Aspergillus nidulans …